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Filtering by: Creator Moore, Dan Remove constraint Creator: Moore, Dan Committee Member Rockey, Dan Remove constraint Committee Member: Rockey, Dan Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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  • Characterization of germination of Clostridium perfringens spores from various sources

    Creator:
    Alnoman, Maryam M.
    Abstract:
    Clostridium perfringens is a pathogenic anaerobic bacterium able to produce more than 17 toxins, allowing C. perfringins to cause a wide variety of diseases in humans and animals. Beside toxins production, C. perfringens able to form a highly resistance spores can survive in the environments for years. These spores are...
    Resource Type:
    Masters Thesis

  • Biosynthesis studies and mutasynthesis of myxobacterial secondary metabolites

    Creator:
    Knight, Eva W.
    Abstract:
    Myxobacteria represent an interesting class of Gram-negative soil bacteria. These bacteria utilize organic materials from the environment as a food source by the action of their extracellular hydrolytic enzymes. They grow vegetatively in the presence of adequate nutrients. During starvation conditions, however, they aggregate and form multicellular structures called fruiting...
    Resource Type:
    Masters Thesis

  • Molecular mechanism of germination of Clostridium perfringens spores

    Creator:
    Paredes-Sabja, Daniel
    Abstract:
    Clostridium perfringens is the causative agent of a wide variety of diseases in animals and humans. C. perfringens can produce more than 15 toxins. However, individual strains produce a subset of these toxins. Although a small percentage of C. perfringens isolates (mostly belonging to type A) produce C. perfringens enterotoxin...
    Resource Type:
    Dissertation

  • Molecular characterization of an HIV-1 drug target and antiviral compound development

    Creator:
    Maselko, Maciej
    Abstract:
    The Human Immunodeficiency Virus -1 (HIV-1) has been the source of substantial human misery since it was first discovered in the early 1980s. Despite remarkable progress that has been made towards understanding HIV- 1, there is no cure, no vaccine and life-prolonging therapies are beyond the reach of millions in...
    Resource Type:
    Dissertation
    Full Text:
    commonly occur during intercourse (Shattock & Moore, 2003). Another favorable route is via inflamed or

  • Elevated ceramide levels contribute to the age-associated decline in vascular endothelial nitric oxide : pharmacologic administration of lipoic acid partially restores function

    Creator:
    Smith, Anthony R.
    Abstract:
    The vascular endothelium is a single cell layer that lines the lumen of the entire vasculature. It is the site of synthesis of nitric oxide (NO), a vasodilatory compound synthesized by endothelial nitric oxide synthase (eNOS). NO causes intracellular calcium sequestration of the vascular smooth muscle cells, relaxing and dilating...
    Resource Type:
    Dissertation
    Full Text:
    graduate committee, Drs. Joe Beckman, Charles Boyer, Balz Frei and Dan Rockey. A special thanks is also

  • Advances in expression of heterologous protein products by Streptococcus gordonii

    Creator:
    Warren, Travis Kent
    Abstract:
    Streptococcus gordonii is a bacterial species that naturally colonizes the oral cavity of most healthy humans. It resides in the mouth as an adherent to dental surfaces and, with few exceptions, does not cause disease in individuals it inhabits. It possesses qualities that encourage its use as a vector to...
    Resource Type:
    Dissertation
    Full Text:
    members, Dr. Kevin Jones, Dr. Nancy Kerkvliet, Dr. Dan Rockey, and Dr. John Dilles who generously gave

  • Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

    Creator:
    Everman, Jamie L.
    Abstract:
    Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
    Resource Type:
    Dissertation
    Full Text:
    also like to thank my committee members Dr. Dan Rockey, Dr. Martin Schuster, Dr. Manoj Pastey, Dr

  • Single-Cell Genomics of Uncultivated Marine Bacteria

    Creator:
    Landry, Zachary
    Abstract:
    Historically, the difficulty of obtaining pure cultures of abundant marine microbial plankton has an obstacle to reconstructing the underlying mechanisms of biogeochemistry in the ocean. While a number of dominant marine species from the ocean surface have been cultured, the dominant microbial plankton of the dark ocean proved far more...
    Resource Type:
    Dissertation

  • Vaccinia virus I7L core protein proteinase

    Creator:
    Byrd, Chelsea M.
    Abstract:
    Vaccinia virus (VV) is a large double-stranded DNA virus that is a prototypic member of the orthopoxvirus family. Previous works has showed that three of the major structural proteins found within the mature VV virion core 4a, 4b, and 25K are produced from higher molecular weight precursors at late times...
    Resource Type:
    Dissertation
    Full Text:
    committee members, Dan Arp, Dan Rockey, Walt Ream, and Luiz Bermudez for constructive criticism, freedom

  • Clostridium perfringens sporulation and gliding motility

    Creator:
    Huang, I-Hsiu
    Abstract:
    Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
    Resource Type:
    Dissertation
    Full Text:
    . Also many thanks to my committee members, Dr. Luiz Bermudez, Dr. Claudia Hase, Dr. Emily Ho, Dr. Dan