Index Catalog // ScholarsArchive@OSU

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Creator:: Simon, Benjamin E.
Abstract:: Several systems were examined for the production and delivery of recombinant vaccines for fish. C. crescentus was employed to produce a fragment of the IHNV glycoprotein. When administered by injection to 0.5 gram rainbow trout (Oncorhynchus mykiss), one of the fusion proteins (184 amino acids of the IHNV glycoprotein fused...
Resource Type:: Dissertation
Full Text:: strains: Differential staining 131 4.4 Invasiveness of I'. ruckeri strains: Gentamicin protection assay

Analysis of Betta splendens erythrophore responses to Bacillus cereus cultured in different media

Creator:: Austin, Melissa J.
Abstract:: Biological agents and their products commonly cause foodborne illnesses. In the United States it is estimated that there are over 76 million cases of foodborne illnesses each year, resulting in an economic loss of approximately $40 billion. These high figures demonstrate the need for bioassays that display a rapid and...
Resource Type:: Masters Thesis
Full Text:: . This sensitivity is equivalent to that expected of the sensitivity pertinent to food safety standards

New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

Creator:: Banawas, Saeed S.
Abstract:: C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
Resource Type:: Dissertation
Full Text:: of Non-Food- Borne Clostridium perfringens Strain F4969 4.1. Abstract

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Creator:: Lewis, Matthew S.
Abstract:: Mycobacterium avium subspecies hominissuis (MAH) is an opportunistic pathogen that is ubiquitous in the environment and often isolated from faucets and showerheads. MAH mostly infects humans with an underlying disease, such as chronic pulmonary disorder (COPD), cystic fibrosis (CF), or are immunocompromised, though infections in patients without concurrent disease are...
Resource Type:: Masters Thesis
Full Text:: resistant to many antibiotics due to the impermeability of its envelope and the protection of its

Characterization of an inhibitor ("6S") of infectious pancreatic necrosis virus (IPNV) in normal rainbow trout serum (RTS) and its effects on the virus

Creator:: Park, Kyoung Chul
Abstract:: The characteristics of an inhibitor of infectious pancreatic necrosis virus (IPNV) found in normal rainbow trout serum (RTS) were studied. The serum inhibitor had a molecular weight of approximately 150 kDa and was dependent on divalent cations, either Ca²⁺ or Mg²⁺. It was stable at temperatures up to 50°C and...
Resource Type:: Dissertation
Full Text:: signs of the disease include lack of any food in the gut, which contains a clear milky mucus in the

Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

Creator:: Babrak, Lmar
Abstract:: Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
Resource Type:: Dissertation
Full Text:: resulted in the protection of interior second bacterial population from exposure to nitric oxide. The

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE DISSERTATION OF Jayanthi J. Joseph for the degree of Doctor of Philosophy in

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: establishment of nutrient delivery to developing bacteria and the second is the protection of the inclusion

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

Creator:: Chinison, Jessica J.
Abstract:: Cases of pulmonary diseases caused by Mycobacterium avium complex (MAC) have increased over the years and have become a major health concern in Europe, Asia, and the United States. MAC, comprised of M. avium species and M. intracellulare, are found everywhere in the environment: in water sources and the soil....
Resource Type:: Masters Thesis
Full Text:: contaminated water and food or inhalation of contaminated water droplets or dust, healthy individuals rarely

Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

Creator:: Rose, Sasha J.
Abstract:: Respiratory infections caused by nontuberculous mycobacteria (NTM), especially Mycobacterium avium, can lead to progressive, recurrent disease that is refractory to therapy. Bacterial biofilms are intrinsically resistant to a variety of stressors and pressures, including host killing mechanisms and antibiotic therapy. Though it is becoming increasingly evident that NTM biofilms are...
Resource Type:: Dissertation
Full Text:: transcription factors are essential for protection to NTM, as individuals with defects in many parts of this

ScholarsArchive@OSU

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Analysis of Betta splendens erythrophore responses to Bacillus cereus cultured in different media

New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Characterization of an inhibitor ("6S") of infectious pancreatic necrosis virus (IPNV) in normal rainbow trout serum (RTS) and its effects on the virus

Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

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