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Filtering by: Creator Stewart, Hugh J. Remove constraint Creator: Stewart, Hugh J. Committee Member Rockey, Daniel Remove constraint Committee Member: Rockey, Daniel License All rights reserved Remove constraint License: All rights reserved

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  • Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

    Creator:
    McNamara, Michael J.
    Abstract:
    Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF Michael J

  • Inactivation Strategy for Clostridium perfringens Spores Adhered onto Stainless Steel Surfaces

    Creator:
    Alzubeidi, Yasmeen S.
    Abstract:
    Clostridium perfringens is a spore-forming pathogenic bacterium that causes a variety of diseases in human and animals. C. perfringens type A isolates produce enterotoxin (CPE) causing food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) diseases including antibiotic-associated diarrhea and sporadic diarrhea. C. perfringens type A food poisoning currently ranks as...
    Resource Type:
    Masters Thesis

  • Infectious diseases of the Felidae : parasite communities from miniature to massive

    Creator:
    Broughton, Heather M.
    Abstract:
    Direct anthropogenic stressors have caused drastic declines in wildlife populations over the past two centuries. In the face of these threats, spillover of infectious disease from domestic animals and livestock into wildlife, and novel interactions between parasites and pathogens within wildlife communities, have further suppressed already vulnerable populations. As management...
    Resource Type:
    Dissertation
    Full Text:
    Veterinary Medicine (OSU CVM) and the LL-Stewart Foundation; and to the OSU CVM class of 2013 for their

  • The Inhibitory Activity of Essential Oil Constituents Against Clostridium perfringens Type A Isolates

    Creator:
    Alanazi, Saud
    Abstract:
    C. perfringens type A isolates are the causative agents of C. perfringens type A food poisoning (FP) and non-food-borne (NFB) human gastrointestinal diseases. In this study, we evaluated the antimicrobial effect of essential oil constituents (cinnamaldehyde, eugenol, allyl isothiocyanate (AITC), and carvacrol) against C. perfringens FP and NFB isolates grown...
    Resource Type:
    Masters Thesis
    Full Text:
    , Saucier, & Lacroix, 2006; Smith-Palmer, Stewart, & Fyfe, 1998). Essential oils are volatile and

  • Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

    Creator:
    Babrak, Lmar
    Abstract:
    Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
    Resource Type:
    Dissertation
    Full Text:
    molecules, homoserine lactone signaling molecules (Costerton, Stewart et al. 1999). Many clinical cases

  • Evolutionary Genomic Responses to Mitochondrial Dysfunction in Caenorhabditis elegans

    Creator:
    Wernick, Riana I.
    Abstract:
    Understanding the impact of mitochondrial dysfunction on genome evolution has the potential not only to provide new insights on the basic evolutionary processes influencing mitochondrial and nuclear genomes, but may also reveal novel avenues for evolutionary adaptive recovery from harmful mutations. Aberrant mitochondrial activity is fundamental to the pathology of...
    Resource Type:
    Dissertation
    Full Text:
    (Alberts B, Johnson A, Lewis J, 2002; Wallace, 2005). Complex V (commonly referred to as ATP Synthase

  • New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

    Creator:
    Banawas, Saeed S.
    Abstract:
    C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
    Resource Type:
    Dissertation

  • Molecular and cellular characterization of the intracellular phenotype of Mycobacterium avium

    Creator:
    Early, Julie V.
    Abstract:
    Mycobacterium avium cause disseminated disease in immunocompromised people such as AIDS patients. Subsequent to crossing the intestinal epithelium, M. avium thrive within vacuoles in macrophages. The bacteria exhibit a different, more invasive, phenotype after being in macrophages compared to M. avium from laboratory conditions. We hypothesized that this intracellular phenotype...
    Resource Type:
    Dissertation
    Full Text:
    . Infect Immun. 1983 Jun;40(3):1155-62. Bhattacharyya A, Pathak S, Basak C, Law S, Kundu M, Basu J

  • Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

    Creator:
    Alhabeeb, Rabiaa
    Abstract:
    Clostridium perfringens is a spore-forming anaerobic organism that is commonly present in fresh meat and poultry. The organism's spores can survive a range of food processing methods. C. perfringens type F isolates are the causative agents of C. perfringens type F food poisoning (FP) and non-food borne (NFB) human gastrointestinal...
    Resource Type:
    Masters Thesis
    Full Text:
    active site and an alpha- sandwich C-terminal domain that is responsible for membrane binding ((J

  • Investigation of unique marine environments for microbial natural products

    Creator:
    Thornburg, Christopher C.
    Abstract:
    Metagenomics has revealed that the marine microbial biosphere is immensely more diverse than originally considered, and is an almost untapped reservoir for the potential discovery of microbial natural products. Despite numerous advances in culturing, biosynthetic engineering and genomic-based screening efforts to uncover much of this diversity in relatively accessible environments,...
    Resource Type:
    Dissertation
    Full Text:
    : Thornburg, C. C., Thimmaiah, M., Shaala, L. A., Hau, A. M., Malmo, J. M., Ishmael, J. E., Youssef, D. T