Index Catalog // ScholarsArchive@OSU

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: Daniel D. Rockey The majority of our modern understanding of bacterial pathogenesis is

Characterization of a Sporulation-Specific Kinase in Clostridium perfringens

Creator:: Danielson, Bryan
Abstract:: Clostridium perfringens type A isolates produce the spore-specific enterotoxin, CPE, upon sporulation in the gastrointestinal tract of humans and animals. Spo0A is a response regulator representing the major transcription factor for sporulation initiation in C. perfringens. In Bacillus subtilis, a multicomponent phosphorelay involving five histidine kinases (KinA-KinE), the intermediate response...
Resource Type:: Undergraduate Thesis and Presentation

The Inhibitory Activity of Essential Oil Constituents Against Clostridium perfringens Type A Isolates

Creator:: Alanazi, Saud
Abstract:: C. perfringens type A isolates are the causative agents of C. perfringens type A food poisoning (FP) and non-food-borne (NFB) human gastrointestinal diseases. In this study, we evaluated the antimicrobial effect of essential oil constituents (cinnamaldehyde, eugenol, allyl isothiocyanate (AITC), and carvacrol) against C. perfringens FP and NFB isolates grown...
Resource Type:: Masters Thesis
Full Text:: Mahfuzur R. Sarker Clostridium perfringens is a gram-positive spore forming bacterium that

Inactivation Strategy for Clostridium perfringens Spores Adhered onto Stainless Steel Surfaces

Creator:: Alzubeidi, Yasmeen S.
Abstract:: Clostridium perfringens is a spore-forming pathogenic bacterium that causes a variety of diseases in human and animals. C. perfringens type A isolates produce enterotoxin (CPE) causing food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) diseases including antibiotic-associated diarrhea and sporadic diarrhea. C. perfringens type A food poisoning currently ranks as...
Resource Type:: Masters Thesis
Full Text:: : Mahfuzur R. Sarker Clostridium perfringens is a spore-forming pathogenic bacterium that causes a

New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

Creator:: Banawas, Saeed S.
Abstract:: C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
Resource Type:: Dissertation
Full Text:: . CONTRIBUTION OF AUTHORS Chapter 2: Dr. Mahfuzur R. Sarker and Dr. Daniel Paredes-Sabja contributed to the

Clostridium perfringens spores : inactivation, germination, and formation

Creator:: Udompijitkul, Pathima
Abstract:: The enterotoxin-producing Clostridium perfringens type A isolates are responsible for the third most common foodborne illness in the United States and can also cause non-foodborne human gastrointestinal (GI) diseases such as antibiotic- associated and sporadic diarrheas. Three important factors contribute to the ability of C. perfringens to cause GI diseases,...
Resource Type:: Dissertation
Full Text:: : __________________________________________________________________ Mahfuzur R. Sarker The enterotoxin-producing Clostridium perfringens type A isolates are

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

Creator:: Alhabeeb, Rabiaa
Abstract:: Clostridium perfringens is a spore-forming anaerobic organism that is commonly present in fresh meat and poultry. The organism's spores can survive a range of food processing methods. C. perfringens type F isolates are the causative agents of C. perfringens type F food poisoning (FP) and non-food borne (NFB) human gastrointestinal...
Resource Type:: Masters Thesis
Full Text:: Abstract approved: ______________________________________________________ Mahfuzur R. Sarker

Evolutionary Genomic Responses to Mitochondrial Dysfunction in Caenorhabditis elegans

Creator:: Wernick, Riana I.
Abstract:: Understanding the impact of mitochondrial dysfunction on genome evolution has the potential not only to provide new insights on the basic evolutionary processes influencing mitochondrial and nuclear genomes, but may also reveal novel avenues for evolutionary adaptive recovery from harmful mutations. Aberrant mitochondrial activity is fundamental to the pathology of...
Resource Type:: Dissertation
Full Text:: elegans Abstract approved: ______________________________________________________ Dee R. Denver

Structural studies of the antioxidant defense enzymes; copper, zinc superoxide dismutase and alkyl hydroperoxide reductase flavoprotein

Creator:: Roberts, Blaine R.
Abstract:: Oxygen derived radicals are involved in many aspects of life from aging and cell signaling to disease states as diverse as heart disease, diabetes, neurodegeneration and inflammation. Therefore, understanding the function of antioxidant defense proteins and the effects of oxygen derived radicals on protein function is essential to elucidate the...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Blaine R. Roberts for the degree of Doctor of Philosophy in

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Creator:: Simon, Benjamin E.
Abstract:: Several systems were examined for the production and delivery of recombinant vaccines for fish. C. crescentus was employed to produce a fragment of the IHNV glycoprotein. When administered by injection to 0.5 gram rainbow trout (Oncorhynchus mykiss), one of the fusion proteins (184 amino acids of the IHNV glycoprotein fused...
Resource Type:: Dissertation
Full Text:: graduate committee members, especially Dr. Lyle Brown and Dr. Daniel Rockey, for stimulating discussions

ScholarsArchive@OSU

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Characterization of a Sporulation-Specific Kinase in Clostridium perfringens

The Inhibitory Activity of Essential Oil Constituents Against Clostridium perfringens Type A Isolates

Inactivation Strategy for Clostridium perfringens Spores Adhered onto Stainless Steel Surfaces

New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

Clostridium perfringens spores : inactivation, germination, and formation

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

Evolutionary Genomic Responses to Mitochondrial Dysfunction in Caenorhabditis elegans

Structural studies of the antioxidant defense enzymes; copper, zinc superoxide dismutase and alkyl hydroperoxide reductase flavoprotein

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

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