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Filtering by: Creator McNamara, Michael Remove constraint Creator: McNamara, Michael Committee Member Rockey, Daniel Remove constraint Committee Member: Rockey, Daniel

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  • Molecular and cellular characterization of the intracellular phenotype of Mycobacterium avium

    Creator:
    Early, Julie V.
    Abstract:
    Mycobacterium avium cause disseminated disease in immunocompromised people such as AIDS patients. Subsequent to crossing the intestinal epithelium, M. avium thrive within vacuoles in macrophages. The bacteria exhibit a different, more invasive, phenotype after being in macrophages compared to M. avium from laboratory conditions. We hypothesized that this intracellular phenotype...
    Resource Type:
    Dissertation
    Full Text:
    Wu, Marta Hearn, Sandra Sommer, Michael McNamara, Kerrigan Gilbert, Sasha Rose and Rachel Tennant

  • Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

    Creator:
    McNamara, Michael J.
    Abstract:
    Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
    Resource Type:
    Dissertation
    Full Text:
    . ©Copyright by Michael J. McNamara March 14, 2012 All Rights Reserved Surface

  • Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

    Creator:
    Babrak, Lmar
    Abstract:
    Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
    Resource Type:
    Dissertation
    Full Text:
    , Jessica Chinison, Dr. Michael McNamara, Val Elias, Laura Hauk, and Mathew Lewis. To all the students I

  • Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

    Creator:
    Rose, Sasha J.
    Abstract:
    Respiratory infections caused by nontuberculous mycobacteria (NTM), especially Mycobacterium avium, can lead to progressive, recurrent disease that is refractory to therapy. Bacterial biofilms are intrinsically resistant to a variety of stressors and pressures, including host killing mechanisms and antibiotic therapy. Though it is becoming increasingly evident that NTM biofilms are...
    Resource Type:
    Dissertation
    Full Text:
    to Michael McNamara, who trained me initially as an undergrad and both taught me essential