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  • The role of Salmonella typhimurium type three secretion system (T3SS) and effector proteins in chromatophore cell response.

    Creator:
    Farhad, Mohammad
    Abstract:
    Bacterial contamination of food poses a great risk to human health worldwide. A chromatophore cell-based biosensor, utilizing B. splendens erythrophore cells, is an emerging technology that has shown potential to detect bacterial toxicity based on function-dependent mechanisms. Previous studies have investigated the response of erythrophore cells to foodborne pathogens, pesticides,...
    Resource Type:
    Masters Thesis
    Full Text:
    Bacterial contamination of food poses a great risk to human health worldwide. A chromatophore cell-based

  • Bacterial Predation in Host Microbiomes

    Creator:
    Welsh, Rory M.
    Abstract:
    In host-associated microbiomes, the mechanisms that regulate community composition or the principles that govern dynamics remain far from clear. However, understanding how the structure of microbial communities shift as the system moves away from a healthy state is critical to assessing disease progression and to formulate any potential mitigation strategy....
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF Rory M. Welsh for the degree of Doctor of Philosophy in

  • Chromatophores as cell-based biosensors for the detection of chemically and biologically toxic substances

    Creator:
    Dukovcic, Stephanie R.
    Abstract:
    Cell-based biosensors are function-based detectors that use the physiological response of a living cell to sense biologically stimulating agents. This emerging technology extends the application of current detection methods by reporting on the toxicity of a sample and the potential to cause disease. Previously, Betta splendens erythrophores have been described...
    Resource Type:
    Dissertation
    Full Text:
    food- and water-based analyses. Chromatophores have emerged as an intriguing class of cell-based

  • Investigating Vibrio parahaemolyticus interactions with the Pacific oyster, Crassostrea gigas

    Creator:
    Aagesen, Alisha M.
    Abstract:
    Vibrio parahaemolyticus is a Gram-negative, halophilic, human pathogenic bacterium ubiquitous in the marine environment. Like many Vibrio species, V. parahaemolyticus commonly associates with shellfish, particularly oysters. Ingestion of a raw or under cooked oysters contaminated with V. parahaemolyticus can cause gastroenteritis, which is typically self-limiting and rarely causes death. Globally,...
    Resource Type:
    Dissertation
    Full Text:
    , and Vibrio parahaemolyticus, common causes of food-borne illness (CDC 2011). Unlike many Vibrio

  • Construction of a model organism for performing calcium carbonate precipitation in a porous media reactor

    Creator:
    Kaufman, Megan J.
    Abstract:
    Aquifers are an important storage location and source of fresh groundwater. They may become polluted by a number of contaminants including mobile divalent radionuclides such as strontium-90 which is a byproduct of uranium fission. A method for remediating such divalent radionuclides is sequestration through co-precipitation into calcium carbonate. Calcium carbonate...
    Resource Type:
    Masters Thesis
    Full Text:
    , potable water and the protection of them is a priority. In case contamination occurs, the remediation

  • Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

    Creator:
    Everman, Jamie L.
    Abstract:
    Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
    Resource Type:
    Dissertation
    Full Text:
    (2014) Evaluation of eight live attenuated vaccine candidates for protection against challenge with

  • Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host Factors

    Creator:
    Nutter, Laura
    Abstract:
    Streptococcus pneumoniae and Influenza A Virus both primarily infect the upper respiratory tract, with more severe disease occurring during coinfection than would be caused by either pathogen independently. Until recently, characterization of the interactions between these two pathogens has occurred exclusively in the context of a host or using host-derived...
    Resource Type:
    Masters Thesis
    Full Text:
    multispecies biofilms to gain characteristics typical of individual members such as beta-lactamase protection

  • Biotransformation of 2,4,6-trinitrotoluene by ruminal organisms

    Creator:
    De Lorme, Marthah J. M.
    Abstract:
    2,4,6-Trinitrotoluene (TNT) has been the common munitions used in the world and is an environmental contaminant that is amendable to reductive transformation reactions. The rumen is an extremely reductive environment containing diverse microbial populations. There are 21 pure culture ruminal bacteria species in culture collection, these were tested for the...
    Resource Type:
    Dissertation
    Full Text:
    phytoremediation have been a concern due to the potential of bioaccumulation along the food chain (Susarla et al

  • Impacts of multispecies parasitism on coho salmon (Oncorhynchus kisutch) in Oregon

    Creator:
    Ferguson, Jayde A.
    Abstract:
    Diseases caused by parasites are recognized as significant sources of mortality in wild fish populations. I assessed the impacts of multispecies parasitism on a threatened stock of juvenile coho salmon (Oncorhynchus kisutch). A crucial prerequisite to this research was proper identification of parasites, which can be difficult for species lacking...
    Resource Type:
    Dissertation
    Full Text:
    ABSTRACT OF THE DISSERTATION OF Jayde A. Ferguson for the degree of Doctor of Philosophy in

  • Bacterial pathogens and associated toxins involved in erythrophore cell aggregation

    Creator:
    Hutchison, Janine R.
    Abstract:
    Current detection methods for bacterial contamination rely on structure based detection of proteins and nucleic acids. While these methods are easy to use and reliable, they cannot evaluate the toxicity of a sample and the potential to cause disease. Previously, erythrophore cells derived from Betta splendens had been suggested as...
    Resource Type:
    Dissertation
    Full Text:
    presented in Table 6. Portions of this dissertation have been published in the Journal of Microbial