Index Catalog // ScholarsArchive@OSU

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Creator:: Baarda, Benjamin I.
Abstract:: Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...
Resource Type:: Dissertation
Full Text:: challenged by the gonococcus’s tremendous modulation of its surface proteome, evasion of immune responses

Context matters : assembly and disorder in the regulation of multivalent complexes

Creator:: Jara, Kayla A.
Abstract:: Intrinsically disordered proteins (IDPs), protein regions (IDRs), and protein complexes continue to emerge at the forefront of protein science. Proteins and protein regions lacking specific structure are found in all organisms, and often have vital roles in numerous biological processes. Breaking the well-known structure-function paradigm, the understanding of disorder-based functionality...
Resource Type:: Dissertation
Full Text:: the forefront of protein science. Proteins and protein regions lacking specific structure are found

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation
Full Text:: .............................................................................................. 228 Appendix II: Temporal profiling of the Arabidopsis plasma membrane proteome and transcriptome

TonB-dependent outer-membrane proteins of Pseudomonas fluorescens : diverse and redundant roles in iron acquisition

Creator:: Hartney, Sierra L.
Abstract:: Pseudomonas is a diverse genus of Gram-negative bacteria that includes pathogens of plants, insects, and humans as well as environmental strains with no known pathogenicity. Pseudomonas fluorescens itself encompasses a heterologous group of bacteria that are prevalent in soil and on foliar and root surfaces of plants. Some strains of...
Resource Type:: Dissertation
Full Text:: immersed in science. My advisor Dr. Joyce E. Loper has given her time and energy to help me complete my

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Creator:: Everman, Jamie L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
Resource Type:: Dissertation

Outliers: The Unusual Characteristics of Marine Carbon-Oxidizing Bacterial Cells Adapted to Oligotrophic Conditions

Creator:: Noell, Stephen E.
Abstract:: Oligotrophic bacteria are adapted to low nutrient concentrations. As most of the ocean is oligotrophic (low in nutrients), oligotrophic bacteria thrive in the ocean and make up the majority of planktonic cells. Because of this, oligotrophs are crucial to oceanic nutrient cycles. However, marine oligotrophic bacteria are dwarfed by their...
Resource Type:: Dissertation

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation

Bacterial Predation in Host Microbiomes

Creator:: Welsh, Rory M.
Abstract:: In host-associated microbiomes, the mechanisms that regulate community composition or the principles that govern dynamics remain far from clear. However, understanding how the structure of microbial communities shift as the system moves away from a healthy state is critical to assessing disease progression and to formulate any potential mitigation strategy....
Resource Type:: Dissertation
Full Text:: the Microbiology Department, Oregon State University, Hatfield Marine Science Center’s Mamie

Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

Creator:: Delgado, Hanna
Abstract:: Vibrio bacteria are commonly found in freshwater, marine, and estuarine environments. Members of this genus can exist in commensal relationships with marine animals or as planktonic bacteria, however, they are well known for their roles as pathogens towards humans and animals. In this dissertation, I investigated aspects of host-bacteria relationships...
Resource Type:: Dissertation
Full Text:: influenzae Rd. Science 269, 496–512. https://doi.org/10.1126/science.7542800 Fraser, C.M., Gocayne, J.D

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

Creator:: Carini, Paul J.
Abstract:: Members of the SAR11 clade of heterotrophic α-proteobacteria are ubiquitous and abundant in the world's oceans where they are thought to play a pivotal role in the global carbon cycle. The first SAR11 bacterium cultivated in vitro, 'Candidatus Pelagibacter ubique' HTCC1062 (Ca. P. ubique), was isolated by dilution into sterile...
Resource Type:: Dissertation
Full Text:: grandfather Joseph Horbas. Although not formally educated in science, he is a Naturalist, in the truest

ScholarsArchive@OSU

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Context matters : assembly and disorder in the regulation of multivalent complexes

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

TonB-dependent outer-membrane proteins of Pseudomonas fluorescens : diverse and redundant roles in iron acquisition

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Outliers: The Unusual Characteristics of Marine Carbon-Oxidizing Bacterial Cells Adapted to Oligotrophic Conditions

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Bacterial Predation in Host Microbiomes

Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

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