Index Catalog // ScholarsArchive@OSU

Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host Factors

Creator:: Nutter, Laura
Abstract:: Streptococcus pneumoniae and Influenza A Virus both primarily infect the upper respiratory tract, with more severe disease occurring during coinfection than would be caused by either pathogen independently. Until recently, characterization of the interactions between these two pathogens has occurred exclusively in the context of a host or using host-derived...
Resource Type:: Masters Thesis

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation

Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

Creator:: Delgado, Hanna
Abstract:: Vibrio bacteria are commonly found in freshwater, marine, and estuarine environments. Members of this genus can exist in commensal relationships with marine animals or as planktonic bacteria, however, they are well known for their roles as pathogens towards humans and animals. In this dissertation, I investigated aspects of host-bacteria relationships...
Resource Type:: Dissertation
Full Text:: bacterial coral pathogen. ISME J. 10, 1363–1372. https://doi.org/10.1038/ismej.2015.216 Giubergia, S

Context matters : assembly and disorder in the regulation of multivalent complexes

Creator:: Jara, Kayla A.
Abstract:: Intrinsically disordered proteins (IDPs), protein regions (IDRs), and protein complexes continue to emerge at the forefront of protein science. Proteins and protein regions lacking specific structure are found in all organisms, and often have vital roles in numerous biological processes. Breaking the well-known structure-function paradigm, the understanding of disorder-based functionality...
Resource Type:: Dissertation

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Creator:: Baarda, Benjamin I.
Abstract:: Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...
Resource Type:: Dissertation

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

Creator:: Carini, Paul J.
Abstract:: Members of the SAR11 clade of heterotrophic α-proteobacteria are ubiquitous and abundant in the world's oceans where they are thought to play a pivotal role in the global carbon cycle. The first SAR11 bacterium cultivated in vitro, 'Candidatus Pelagibacter ubique' HTCC1062 (Ca. P. ubique), was isolated by dilution into sterile...
Resource Type:: Dissertation

Bacterial Predation in Host Microbiomes

Creator:: Welsh, Rory M.
Abstract:: In host-associated microbiomes, the mechanisms that regulate community composition or the principles that govern dynamics remain far from clear. However, understanding how the structure of microbial communities shift as the system moves away from a healthy state is critical to assessing disease progression and to formulate any potential mitigation strategy....
Resource Type:: Dissertation
Full Text:: The ISME Journal doi: 10.1038/ismej.2015.219

Construction of a model organism for performing calcium carbonate precipitation in a porous media reactor

Creator:: Kaufman, Megan J.
Abstract:: Aquifers are an important storage location and source of fresh groundwater. They may become polluted by a number of contaminants including mobile divalent radionuclides such as strontium-90 which is a byproduct of uranium fission. A method for remediating such divalent radionuclides is sequestration through co-precipitation into calcium carbonate. Calcium carbonate...
Resource Type:: Masters Thesis

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation

ScholarsArchive@OSU

Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host Factors

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

Context matters : assembly and disorder in the regulation of multivalent complexes

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

Bacterial Predation in Host Microbiomes

Construction of a model organism for performing calcium carbonate precipitation in a porous media reactor

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

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