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Filtering by: Advisor Dolan, Brian Committee Member Shulzhenko, Natalia

Impact of Unfolded Protein Response, USP14, and NEDD8 Inhibitors Upon Antigen Presentation in SaI/Ak and 4T1 Tumor Cell Lines

Creator:

Godil, Jamila A.

Abstract:

Antigen presentation is a mechanism used by cells to present peptides on the cell surface. Peptides, derived from both viral or self-proteins are presented on the cell surface by MHC Class I molecules to be recognized and detected by cytotoxic T cells. T cells comprise the defense system to protect...

Resource Type:

Honors College Thesis

Full Text:

:_____________________________________________________ Brian Dolan Antigen presentation is a mechanism used by cells to present peptides on the
Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:

Nagamine, Brandy S.

Abstract:

The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...

Resource Type:

Dissertation

Full Text:

: _____________________________________________________ Brian P. Dolan The immune system is a complex network of cellular processes working