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Filtering by: Contributor Fernández, Natalia Committee Member Shulzhenko, Natalia

Western Diet-Induced Nonalcoholic Steatohepatitis (NASH): The Impact of Time on the Onset and Remission of Disease

Creator:

Spooner, Melinda H.

Abstract:

Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...

Resource Type:

Dissertation

Full Text:

endeavors of lifelong learning. Next, my committee members Dr. Emily Ho, Dr. Natalia Shulzhenko, Dr
Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:

Nagamine, Brandy S.

Abstract:

The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...

Resource Type:

Dissertation

Full Text:

. I am thankful to my committee members, Dr. Natalia Shulzhenko and Dr. Theresa Filtz, for their
Towards a Better Understanding of How the Dietary Supplement Xanthohumol Can Improve Health

Creator:

Logan, Isabelle E.

Abstract:

Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...

Resource Type:

Dissertation

Full Text:

. Thank you to my advising committee members, Drs. Gerd Bobe, Siva Kolluri, Viviana Pérez, Natalia