Index Catalog // ScholarsArchive@OSU

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Creator:: Hutanu, Daniela
Abstract:: The emerging field of nanotechnology strictly requires the micro-scaling of the available separation technology and the design of novel devices for separations of molecules of interest. The separation of proteins and nanoparticles is challenging due to their relatively large size, non-specific adherence to surfaces and instability in many solvents. This...
Resource Type:: Dissertation
Full Text:: completely. Plate height, HETP, is defined as: HETP = w2L / 16 tR2 16 where w is the

Semiconductor Nanocrystals as Detection Components in Microfluidic Analytical Systems

Creator:: Pengpumkiat, Sumate
Abstract:: Miniaturized and portable microfluidic analytical platforms have been widely explored in the broad field of chemical analysis. The concept of microfluidics offer a number of important advantages, including low reagent consumption, low-cost detection, high sample throughput, and shorter analysis time. Semiconductor nanocrystals or quantum dots have been extensively utilized in...
Resource Type:: Dissertation
Full Text:: ) Reprinted from Current Opinion in Chemical Biology, 10, S. K. Shin, H. Yoon, Y. J. Jung, J. W. Park

Assessing Chemical Dispersants Used During the Deepwater Horizon Oil Spill : Method Innovation and Application

Creator:: Perkins, Matt J.
Abstract:: Large quantities of the chemical oil dispersant Corexit were applied in the Gulf of Mexico (Gulf) in response to the Deepwater Horizon oil spill. Large data gaps regarding the potential transport, persistence and impact of Corexit in the Gulf existed at the time of the emergency response. Analytical methods for...
Resource Type:: Dissertation
Full Text:: -Martínez, R.; Snell, T. W.; Shearer, T. L., Synergistic toxicity of Macondo crude oil and dispersant

Analytical method development for the identification, detection, and quantification of emerging environmental contaminants in complex matrices

Creator:: Place, Benjamin J.
Abstract:: The development of analytical methods for emerging contaminants creates many unique challenges for analytical chemists. By their nature, emerging contaminants have inherent data gaps related to their environmental occurrence, fate, and impact. This dissertation is a compilation of three studies related to method development for the structural identification of emerging...
Resource Type:: Dissertation
Full Text:: . Technol. 1999, 33, (16), 2800-2806. 12 11. Moody, C. A.; Martin, J. W.; Kwan, W. C.; Muir, D. C

Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

Creator:: Zhang, Lulu
Abstract:: Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...
Resource Type:: Dissertation

Poly- and perfluorinated alkyl substance release from landfills and landfill model reactors

Creator:: Allred, Brent McKay
Abstract:: Research and public concern of poly and perfluoroalkyl substances (PFASs) as environmental contaminants has increased significantly due to the increasing number of reports of their detection in humans and wildlife. PFASs have a number of commercial applications including surfactants, coatings, polymers, and levelers, which are used on consumer products like...
Resource Type:: Dissertation

Comprehensive, Low-Cost Wicking Microfluidic Analytical Devices for Clinical Diagnostics and Environmental Analysis

Creator:: Bandara, Gayan C.
Abstract:: Analytical techniques are utilized in a wide variety of applications. Traditionally, analytical measurements are achieved by trained personnel in a laboratory setting using expensive scientific instruments, which limits their applicability in resource-limited areas and point-of-care applications. Therefore, the concept of enabling these laboratory-based qualitative and quantitative assays in microfluidic device...
Resource Type:: Dissertation

Human Exposure to PAHs in Air, Water, and Crayfish

Creator:: Paulik, L. Blair
Abstract:: There are many links between exposure to environmental pollution and risks to human health. While advances in the fields of toxicology, exposure science, and environmental chemistry have shown light on many of these links, many more research challenges remain. One major challenge is how to accurately characterize the toxicity of...
Resource Type:: Dissertation

Per- and Polyfluoroalkyl Substances: From Disposition on Consumer Products and Field Materials to Treatment of Contaminated Groundwater

Creator:: Robel, Alix E.
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are an emerging chemical class of concern. Recently in the United States, Health Advisory Limits for two PFAS in drinking water were established for perfluorooctane sulfonate and perfluorooctanoate in drinking water (set to 70 ng/L combine concentration) by the EPA. Because of PFAS mobility, persistence,...
Resource Type:: Dissertation
Full Text:: . 7. Wang, N.; Liu, J. X.; Buck, R. C.; Korzeniowski, S. H.; Wolstenholme, B. W.; Folsom, P. W

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Creator:: Yang, Liping
Abstract:: The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
Resource Type:: Dissertation

ScholarsArchive@OSU

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Semiconductor Nanocrystals as Detection Components in Microfluidic Analytical Systems

Assessing Chemical Dispersants Used During the Deepwater Horizon Oil Spill : Method Innovation and Application

Analytical method development for the identification, detection, and quantification of emerging environmental contaminants in complex matrices

Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

Poly- and perfluorinated alkyl substance release from landfills and landfill model reactors

Comprehensive, Low-Cost Wicking Microfluidic Analytical Devices for Clinical Diagnostics and Environmental Analysis

Human Exposure to PAHs in Air, Water, and Crayfish

Per- and Polyfluoroalkyl Substances: From Disposition on Consumer Products and Field Materials to Treatment of Contaminated Groundwater

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

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