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Filtering by: Creator Webb, Molly A. H. Remove constraint Creator: Webb, Molly A. H. Committee Member Simonich, Staci Remove constraint Committee Member: Simonich, Staci

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  • Advances in Passive Sampling : Measuring Chemical Transport and Human Exposures

    Creator:
    Donald, Carey E.
    Abstract:
    Passive sampling devices have been used for decades to measure complex mixtures of bioavailable organic chemicals in a variety of environmental media. More recently passive sampler applications have expanded beyond monitoring chemical concentrations, and this dissertation continues to advance methods of passive sampling on many fronts. Despite their growing use,...
    Resource Type:
    Dissertation
    Full Text:
    : Kim A. Anderson Passive sampling devices have been used for decades to measure complex mixtures of

  • Assessing Chemical Dispersants Used During the Deepwater Horizon Oil Spill : Method Innovation and Application

    Creator:
    Perkins, Matt J.
    Abstract:
    Large quantities of the chemical oil dispersant Corexit were applied in the Gulf of Mexico (Gulf) in response to the Deepwater Horizon oil spill. Large data gaps regarding the potential transport, persistence and impact of Corexit in the Gulf existed at the time of the emergency response. Analytical methods for...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Jennifer A. Field Large quantities of the chemical oil dispersant Corexit were applied in

  • Advancement of Passive Sampling Applications for Assessing Contaminant Transport, Bioaccumulation, and Toxicity

    Creator:
    Minick, David J.
    Abstract:
    In the environment, it is the unbound fraction of chemical (Cfree) which is able to diffuse across environmental interfaces and biological membranes. It is therefore Cfree which drives many important biological-environmental processes including contaminant transport, bioaccumulation and toxicity. Passive sampling devices (PSDs) offer a simplified and more accurate approach for...
    Resource Type:
    Dissertation
    Full Text:
    , Bioaccumulation, and Toxicity Abstract approved: Kim A. Anderson In the environment, it is the

  • Human Exposure to PAHs in Air, Water, and Crayfish

    Creator:
    Paulik, L. Blair
    Abstract:
    There are many links between exposure to environmental pollution and risks to human health. While advances in the fields of toxicology, exposure science, and environmental chemistry have shown light on many of these links, many more research challenges remain. One major challenge is how to accurately characterize the toxicity of...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Kim A. Anderson There are many links between exposure to environmental pollution and risks to

  • Determination of fluorochemicals in waste-dominated aqueous systems

    Creator:
    Huset, Carin A.
    Abstract:
    While fluorochemicals have been detected all over the world and in wastewater treatment plants, the effect of wastewater effluent on the receiving waters has not been evaluated. In the first study, the mass flow of fluorochemicals emanating from wastewater treatment plants along the Glatt River in Switzerland was evaluated. The...
    Resource Type:
    Dissertation
    Full Text:
    half-life of 92 ± 10 h.29 PFCAs were degraded photochemically with the aid of a tungstic

  • Development, performance evaluation and application of a physical model of the Kenyan-Tanzanian coastal region

    Creator:
    Mayorga Adame, Claudia Gabriela
    Abstract:
    A Regional Ocean Modeling System (ROMS) application for the coastal region of Kenya and Tanzania (0-10° S, 38.7-46.98° E) was developed with the aim of better resolving the circulation patterns in the coastal region that is poorly represented in global models. The model has a horizontal resolution of 4 km,...
    Resource Type:
    Masters Thesis
    Full Text:
    a Physical Model of the Kenyan-Tanzanian Coastal Region AN ABSTRACT OF THE THESIS OF

  • Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

    Creator:
    Zhang, Lulu
    Abstract:
    Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...
    Resource Type:
    Dissertation
    Full Text:
    provide unparalleled detail on spatial and temporal heterogeneities within a single cell. The ability to

  • Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

    Creator:
    Yang, Liping
    Abstract:
    The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
    Resource Type:
    Dissertation
    Full Text:
    The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription

  • Variability in mesoscale circulation and its effects on zooplankton distribution in the Northern California Current

    Creator:
    Keister, Julie Eileen
    Abstract:
    In eastern boundary current upwelling ecosystems, mesoscale circulation features such as eddies and upwelling filaments play a prominent role in the transfer of water and the associated plankton from the productive nearshore to the oligotrophic deep sea. The relationship between mesoscale circulation, zooplankton distributions, and the across-shelf transport of coastal...
    Resource Type:
    Dissertation
    Full Text:
    filaments play a prominent role in the transfer of water and the associated plankton from the productive

  • Husbandry stress of Zebrafish, Danio rerio

    Creator:
    Ramsay, Jennifer Mara
    Abstract:
    Zebrafish, Danio rerio, are widely used as vertebrate research organisms yet little is know about their responses to husbandry stressors. This dissertation examined the whole-body cortisol responses of zebrafish to husbandry stress. Additionally, the effects of stress on the susceptibility to mycobacteriosis and microsporidiosis (Pseudoloma neurophilia) were determined including effects...
    Resource Type:
    Dissertation
    Full Text:
    , zebrafish rapidly responded to net handling stressors with a 6-fold increase in whole-body cortisol which