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Filtering by: Committee Member Somoza, Carmen Creator Lindquist, Jonathan A. Creator Lindquist, Jonathan A. Decade 1990-1999

1. Automethylation : a response to enzyme aging

Creator:: Lindquist, Jonathan A.
Abstract:: This is the first study to explore the ability of an enzyme to recognize and repair spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM) is known to repair damage that arises from a spontaneous isomerization of aspartyl and asparaginyl residues in other proteins during aging. As...
Resource Type:: Dissertation