Index Catalog // ScholarsArchive@OSU

Correlation of fecal ergovaline, lolitrem B, and their metabolites in steers fed endophyte infected perennial ryegrass straw

Creator:: Murty, Lia D.
Abstract:: Perennial ryegrass (PRG, Lolium perenne) is a hardy cool-season grass that is infected with the endophytic fungus Neotyphodium lolii, which enables the plant to be insect repellant and drought resistant, lowering the use of insecticides and fertilizers. However, this fungus produces the compound lolitrem B (LB, m/z 686.4) which causes...
Resource Type:: Masters Thesis
Full Text:: sincere appreciation to Dr. A. Morrie Craig and Dr. Fred Stevens for serving as my academic advisors and

Biosynthesis studies and mutasynthesis of myxobacterial secondary metabolites

Creator:: Knight, Eva W.
Abstract:: Myxobacteria represent an interesting class of Gram-negative soil bacteria. These bacteria utilize organic materials from the environment as a food source by the action of their extracellular hydrolytic enzymes. They grow vegetatively in the presence of adequate nutrients. During starvation conditions, however, they aggregate and form multicellular structures called fruiting...
Resource Type:: Masters Thesis

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: Freitag, and Dr. Fred Stevens for their advice and help towards the completion of my program. Many

Mechanistic Studies and Catalytic Engineering of the Pseudoglycosyltransferase VldE

Creator:: Abuelizz, Hatem A.
Abstract:: This thesis describes an investigation of the molecular basis of the substrate specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a newly discovered group of glycosyltransferase (GT)-like proteins that catalyze the transfer of a pseudosugar to an acceptor molecule via a C-N bond formation. This...
Resource Type:: Dissertation
Full Text:: work. I also thank my thesis committee members Dr. Mark Zabriskie, Dr. Kerry McPhail, Dr. Fred

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Creator:: Farley, Sherry Mae
Abstract:: The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Resource Type:: Dissertation
Full Text:: spectrometry support provided by Alan Taylor, Fred Stevens, and Jay Kirkwood. I would also like to express my

Spatiotemporal Phytohormone Distributions in Developing Pinot Noir Berries and the Effects of Two Viticulture Practices Thereon

Creator:: Schmidt, Joseph A.
Abstract:: In recent years, many studies have focused on the molecular and biochemical mechanisms regulating the development of wine grapes. The course of grape berry development is directed by genetic design and is mediated by phytohormones, which regulate grape berry growth and development by orchestrating a complex network of interacting genes,...
Resource Type:: Masters Thesis

Programming of Furosemide Pharmacokinetics by Intrauterine Growth Restriction and High Fat Diet in the Adult Rat

Creator:: DuBois, Barent Nathan
Abstract:: Perinatal growth restriction programs higher risk for chronic disease during adulthood via morphological and physiological changes in organ systems. Perinatal growth restriction is highly correlated with a decreased nephron number, altered renal function and subsequent hypertension. I hypothesize that such renal maladaptations result in altered pharmacologic patterns for life. Pregnant...
Resource Type:: Dissertation

A Promising Approach for Preventing of Diet-Induced Obesity and Fatty Liver Using Tetrahydroxanthohumol, A Synthetic Derivative of Xanthohumol

Creator:: Zhang, Yang
Abstract:: Obesity and metabolic syndrome (MetS) affect over 1.9 billion adults and 12.7 million youth in the US. If all of today’s obese American youth become obese adults, the total societal costs over their lifetime may exceed $1.1 trillion. We show that feeding rodents a high-fat diet supplemented with xanthohumol (XN)...
Resource Type:: Dissertation
Full Text:: . To the rest of my committee, Drs. Thomas Sharpton, Fred Stevens, Charlotte Wickham, and Joy Waite

Mass spectrometry-based identification and characterization of protein and peptide adducts of lipoxidation-derived aldehydes

Creator:: Chavez, Juan D.
Abstract:: Oxidative stress is recognized as an important underlying factor in the pathogenesis of many degenerative diseases as well as normal senescence. The free radicals, reactive oxygen species (ROS) and electrophiles produced during oxidative stress are capable of modifying nucleic acids, lipids and proteins. There are a variety of oxidative modifications...
Resource Type:: Dissertation
Full Text:: . Phil Watson, Dr. Manish Gupta, Dr. Larry Daley, and Dr. Fred Stevens. I would also like to thank

Chemical labeling methods and mass spectrometry of mitochondrial thiol proteomes

Creator:: Wang, Jing
Abstract:: Dysfunction of mitochondria has been linked to aging and the pathogenesis of many degenerative diseases. Aside from their primary function in energy production, mitochondria are considered as a major source and target of reactive oxygen and nitrogen species (ROS/RNS) in cells as well. The mitochondrial thiol proteome is a subset...
Resource Type:: Dissertation
Full Text:: , Fred Stevens, Ron Wrolstad and Gregory Rorrer. I would also like to express my appreciation to all

ScholarsArchive@OSU

Correlation of fecal ergovaline, lolitrem B, and their metabolites in steers fed endophyte infected perennial ryegrass straw

Biosynthesis studies and mutasynthesis of myxobacterial secondary metabolites

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Mechanistic Studies and Catalytic Engineering of the Pseudoglycosyltransferase VldE

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Spatiotemporal Phytohormone Distributions in Developing Pinot Noir Berries and the Effects of Two Viticulture Practices Thereon

Programming of Furosemide Pharmacokinetics by Intrauterine Growth Restriction and High Fat Diet in the Adult Rat

A Promising Approach for Preventing of Diet-Induced Obesity and Fatty Liver Using Tetrahydroxanthohumol, A Synthetic Derivative of Xanthohumol

Mass spectrometry-based identification and characterization of protein and peptide adducts of lipoxidation-derived aldehydes

Chemical labeling methods and mass spectrometry of mitochondrial thiol proteomes

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search