Index Catalog // ScholarsArchive@OSU

Creator:: Sanchez, Karina M.
Abstract:: Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...
Resource Type:: Undergraduate Thesis
Full Text:: (NIFA) which is part of the US Department of Agriculture (USDA) and Dr. Fred Stevens’ OSU College of

Creator:: Plagmann, Layhna S.
Abstract:: Xanthohumol [XN, (E)-6´-methoxy-3´-(3-methylbuten-2-yl)-2´,4´,4´´-trihydroxychalcone], the principal prenylated chalcone from hops, and its 2,3-dihydro- (DXN) and O6-desmethyl-2,3-dihydro- (DDXN) congeners, are of potential utility for the amelioration of metabolic syndrome; however, their complex bioactivity profiles cannot be properly studied and understood without access to appropriately produced synthetic materials. In the first part of...
Resource Type:: Masters Thesis
Full Text:: possible; Prof. Fred Stevens, for his continued passion toward this project; Dr. Daniel Myles

Creator:: Lattier, Vera C.
Abstract:: Skeletal muscle, the largest organ in the body in mass, is composed by 600 specialized muscles in humans with unique biochemical, physiological and metabolic identities. Skeletal muscles control body movement, locomotion, and nutrient balance. Muscle formation requires precisely orchestrated environmental signals and regulatory gene networks in time and space. Gene...
Resource Type:: Dissertation
Full Text:: this far without her. I thank my committee member Dr. Barbara Taylor, Dr. Fred Stevens, Dr. Mark

Creator:: Carpenter, Evan L.
Abstract:: Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Resource Type:: Dissertation
Full Text:: . Ralph L. Reed conceptualized and conducted the experiments done by the Stevens Lab. Dr. Fred Stevens

Creator:: Intanon, Suphannika
Abstract:: Meadowfoam (Limnanthes alba Hartw. ex Benth) seed meal (MSM), a by-product of meadowfoam oil extraction, has a plant defensive compound known as glucosinolate glucolimnanthin (GLN). Myrosinase enzymes present in soil microbes and meadowfoam seeds can convert GLN to glucosinolate breakdown products (GBPs), which demonstrate herbicidal activity and have the potential...
Resource Type:: Dissertation
Full Text:: . Jennifer Kling for her advice and statistical support. Thanks also to Dr. Fred Stevens for his assistance

Creator:: Tzeng, Shin-Cheng
Abstract:: Alcoholic liver disease (ALD) continues to be one of the major public health problems in the United States and worldwide. Complicated by factors including gender, polymorphisms of alcohol-metabolizing enzymes, immunologic factors, exposures to other substances/drugs, hepatic viral infections, nutritional deficiencies, and obesity, ALD is a complex disease that requires a...
Resource Type:: Dissertation
Full Text:: : Professors Tory Hagen, Fred Stevens, Victor Hsu and Neal Sleszynski. I would also like to express my

Creator:: Denluck, Lindsay
Abstract:: Nanoparticles (NPs), defined as materials having at least one dimension (height, width, diameter) in the nanoscale, are increasingly being incorporated into a wide variety of products and are replacing traditional bulk materials in many applications. This is because they can be more efficacious, more sustainable, and can have unique characteristics...
Resource Type:: Dissertation
Full Text:: Tanguay, Dr. Craig Marcus, Dr. Fred Stevens, Dr. Siva Kolluri, and Dr. Tyler Radniecki for providing me

Creator:: Bouranis, John A.
Abstract:: Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...
Resource Type:: Dissertation
Full Text:: members Dr. Norm Hord, Dr. Maret Traber, Dr. Susan Tilton, and Dr. Fred Stevens – thank you for your

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