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Filtering by: Creator Doddapaneni, Bhuvana Shyam Committee Member Taratula, Oleh Language English [eng]

Development of Micellar and Nanoparticle Structures based on Polyester Diblock Copolymer Platform for the Treatment of Metastatic Tumors

Creator:

Doddapaneni, Bhuvana S.

Abstract:

Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...

Resource Type:

Dissertation

Full Text:

Bhuvana S. Doddapaneni for the degree of Doctor of Philosophy in Pharmacy presented on June 9, 2016
Development of thermosensitive injectable hydrogel and transdermal controlled release formulations for Tacrolimus

Creator:

Nguyen, Duc X.

Abstract:

TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...

Resource Type:

Dissertation