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Filtering by: Creator Palma, Elbio D. Committee Member Taylor, Barbara Non-Academic Affiliation Oregon State University. Graduate School

Oxidative stress in amyotrophic lateral sclerosis : the role of cellular senescence and glutathione

Creator:

Beilby, Pamela R.

Abstract:

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by neuromuscular junction decay, motor neuron death, progressive paralysis, and eventually death of the individual, usually by respiratory failure. Oxidative stress is a prominent hallmark of the disease and is often accompanied and exacerbated by mitochondrial dysfunction and neuroinflammation. This...

Resource Type:

Dissertation
Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:

Norby, Tyler S.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...

Resource Type:

Masters Thesis

Full Text:

)pyrene Dibenz(α,h)anthracene Dibenz(α,j)anthracene Dibenz(α,c)anthracene Cyclopenta(c,d)pyrene Pentacene
Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:

Fox, Samuel E.

Abstract:

Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...

Resource Type:

Dissertation

Full Text:

R. Christie, Henry D. Priest and Doug W. Bryant analyzed the data. Samuel E. Fox, Mark R. Christie

ScholarsArchive@OSU

Oxidative stress in amyotrophic lateral sclerosis : the role of cellular senescence and glutathione

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

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