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Filtering by: Creator Ogawa Abe, Tania Marie Remove constraint Creator: Ogawa Abe, Tania Marie Committee Member Taylor, Barbara Remove constraint Committee Member: Taylor, Barbara

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  • Oxidative stress in amyotrophic lateral sclerosis : the role of cellular senescence and glutathione

    Creator:
    Beilby, Pamela R.
    Abstract:
    Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by neuromuscular junction decay, motor neuron death, progressive paralysis, and eventually death of the individual, usually by respiratory failure. Oxidative stress is a prominent hallmark of the disease and is often accompanied and exacerbated by mitochondrial dysfunction and neuroinflammation. This...
    Resource Type:
    Dissertation

  • Gene expression in the peripartum canine placenta

    Creator:
    Fellows, Elizabeth Jane
    Abstract:
    This research investigated gene expression in the canine placenta during the peripartum period. Previous studies have recognized molecular changes that occur in the placenta around the time of placental release in other species, but no study has looked at gene expression in the late gestation canine placenta. Of particular significance...
    Resource Type:
    Masters Thesis
    Full Text:
    -Marie Girard for her help with microarray. I would also like to thank Dr. Gerd Bobe and Dr. Yanming Di