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Filtering by: Alternative title ssim EC 1196 Committee Member Taylor, Barbara

Analysis of chlamydial and host proteins associated with infection

Creator:

Chu, Hencelyn

Abstract:

Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...

Resource Type:

Dissertation
Three Sites are Better than One : Exploring Multivalency in LC8 Binding Partners

Creator:

Clark, Sarah A.

Abstract:

Hub proteins bind a large number of partners to facilitate structural changes and downstream protein interactions. LC8, a highly conserved protein homodimer, is a unique hub that regulates the activity of proteins in a wide range of cellular processes by binding to intrinsically disordered regions. With many of these systems,...

Resource Type:

Dissertation
Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:

Fox, Samuel E.

Abstract:

Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...

Resource Type:

Dissertation