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Filtering by: Creator Gartner, Barbara L. Remove constraint Creator: Gartner, Barbara L. Committee Member Taylor, Barbara Remove constraint Committee Member: Taylor, Barbara

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  • Adaptation to long-term osmotic stress in a domesticated Saccharomyces cerevisiae strain

    Creator:
    Holman, Douglas S.
    Abstract:
    Osmotic stress is a common challenge faced by organisms in environments with variable salinity or aridity. Understanding the evolutionary mechanisms underlying adaptation to osmotic stress may have wide applications, including management of populations experiencing climate change, or engineering industrial organisms involved in processes such as fermentation. While Saccharomyces cerevisiae is...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Barbara Taylor, Committee Member, representing Integrative Biology

  • Analysis of chlamydial and host proteins associated with infection

    Creator:
    Chu, Hencelyn
    Abstract:
    Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Luiz Bermudez, Dr. Mahfuz Sarker, Dr. Karen Guillemin, and Dr. Barbara Taylor who all have an

  • Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

    Creator:
    Norby, Tyler S.
    Abstract:
    Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
    Resource Type:
    Masters Thesis
    Full Text:
    , Dr. Michael Burgett, Dr. Lawrence Curtis and Dr. Barbara Taylor). Second is my labmates (Claudia

  • Biologically active metabolites from marine microorganisms : methods to identify drug leads and chemical signals

    Creator:
    Vining, Oliver B.
    Abstract:
    Microbial natural products represent a massive repository of unique chemical scaffolds with corresponding diverse biological functions. However, in the past decade the development of natural products into new therapeutics has dwindled, in part due to the challenges posed by high rediscovery rates and low throughput associated with classical bioassay-guided fractionation...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Kerry L. McPhail Microbial natural products represent a massive repository of unique

  • Biosynthesis and Rational Design of Novel Pactamycin Analogs

    Creator:
    Abugrain, Mostafa E.
    Abstract:
    Pactamycin, a potent antitumor antibiotic produced by the soil bacterium Streptomycespactum, is a structurally unique aminocyclopentitol-containing natural product. Itconsists of a highly functionalized cyclopentitol core unit, two aromatic rings [3-aminoacetophenone (3AAP) and 6-methylsalicylic acid (6MSA)], and a 1,1-dimethylurea moiety. Despite its potent biological activity, the development of thisantibiotic was hampered...
    Resource Type:
    Dissertation
    Full Text:
    work. I would like to thank my committee members Dr. Barbara Taylor, Dr. Mark Zabriskie, Dr

  • Cellular characteristics of canine trophoblasts

    Creator:
    Sahlfeld, Laura
    Abstract:
    This research investigated the development of a novel canine model to study preeclampsia. Normal canine placental development has morphologic and histologic similarities to the shallow trophoblast invasion occurring with preeclampsia in humans, which makes the dog a particularly good choice for modeling this disease and will be an improvement on...
    Resource Type:
    Masters Thesis
    Full Text:
    , G., Yamamoto, S., Lowndes, K., Webster, L., Parg, S., Amano, A., 2005. Human decidual relaxin and

  • Cellular Recognition, Division, and Proliferation in the Cnidarian-Dinoflagellate Symbiosis

    Creator:
    Tivey, Trevor R.
    Abstract:
    Cnidarians and their symbiotic dinoflagellates form a productive mutualism that shapes marine environments. In this symbiosis, dinoflagellate species from the family Symbiodiniacea reside within cnidarian host gastrodermal cells and provide the host with photosynthetically fixed carbon in exchange for host metabolites. This nutritional exchange allows both partners to thrive in...
    Resource Type:
    Dissertation
    Full Text:
    Page Appendix Figure A1. Lectin specificity of MVL, CVN, and PHA-L. ........................... 140

  • Characterization of the Zea mays ssp. mays TOUSLED-like kinases

    Creator:
    Owusu, Ethel Owusuwaa
    Abstract:
    This dissertation describes the cloning and characterization of the TOUSLEDlike kinases genes of maize (ZmTLKs). The TOUSLED-like kinases (TLKs) are a conserved family of nuclear Ser/Thr kinases in higher eukaryotes. The maize genome has three TOUSLED-like kinase genes (ZmTLK1, ZmTLK2, and ZmTLK3). Based upon sequence similarity, the ZmTLKs are divided...
    Resource Type:
    Dissertation
    Full Text:
    : Characterization of the Zea mays ssp. mays TOUSLED-Like Kinases Abstract aPProve L ( - carøiI Rivin This

  • Characterizing Mycobacterium avium subspecies hominissuis (MAH) Microaggregate Induction of Innate Immunity

    Creator:
    Keefe, Bailey F.
    Abstract:
    Bacterial aggregation is a strategy employed by many pathogens to establish infection. Mycobacterium avium subsp. hominissuis (MAH) undergoes a phenotypic change, microaggregation, when exposed to the respiratory epithelium. This aggregation is an important step in the pathogenesis of the infection, laying the foundation for biofilm formation. We therefore compared how...
    Resource Type:
    Masters Thesis
    Full Text:
    , Rigouts L, Mijs W, Portaels F, de Haas P, van Soolingen D, Van der Laan T. 2002. Molecular evidence to

  • Community profiles of ammonia oxidizers across high-elevation forest-to-meadow transects

    Creator:
    Mintie, Ann
    Abstract:
    In recent years considerable interest has been shown in the diversity of ammonia-oxidizing bacteria in soil communities. The majority of the research has been carried out in Northern Europe where soils have received high atmospheric inputs of nitrogen over the past two centuries. In contrast, although much work has been...
    Resource Type:
    Masters Thesis
    Full Text:
    for you both as a scientist and a person. Dr. Barbara Taylor, for taking me under your Drosophila