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Filtering by: Subject DNA-protein interactions Remove constraint Subject: DNA-protein interactions Committee Member Taylor, Barbara J. Remove constraint Committee Member: Taylor, Barbara J.

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  • Organization of the T4 dNTP synthetase complex at DNA replication sites

    Creator:
    Kim, JuHyun
    Abstract:
    With respect to a multienzyme complex of deoxyribonucleoside triphosphate (dNTP) synthesis somehow juxtaposed with DNA replication sites, our laboratory has demonstrated the existence of a multienzyme complex in T4-infected E. coli, named the T4 dNTP synthetase complex, but the idea of direct linkage of dNTP synthesis to DNA replication and...
    Resource Type:
    Dissertation
    Full Text:
    , the single-stranded DNA binding protein encoded by gene 32, plays a role in recruiting enzymes of

  • Protein Disorder in the Evolution of Dynein Regulation

    Creator:
    Jie, Jing
    Abstract:
    Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
    Resource Type:
    Dissertation
    Full Text:
    , and the DNA damage repair protein Rad50 (Mark et al., 6 2005; Uversky et al., 2008

  • Characterization of the Structure and Dynamics of the Intrinsically Disordered Dynein Intermediate Chain and its Interactions with Regulatory Binding Partners

    Creator:
    Morgan, Jessica L.
    Abstract:
    Cells represent microcosms of spatial and temporal structural organization, with the achievement of internal spatial organization relying upon a collection of macromolecular motor complexes to transport and localize components throughout the cell. Cytoplasmic dynein is one such motor complex, and is the principal ATP-dependent motor for retrograde transport along microtubules...
    Resource Type:
    Dissertation
    Full Text:
    ) DNA-binding domain of the CREB (cyclic AMP response element-binding protein) transcription factor