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Filtering by: Creator Egeland%2C Dawn M. Committee Member Turner, Russell Degree Level Bachelor's

Effects of Spaceflight on Cancellous and Cortical Bone in Proximal Femur in Rats

Creator:

Gamboa, Amanda R.

Abstract:

Bone loss is common in astronauts during long-duration spaceflight missions with severe bone loss often occurring in the proximal femur, a region not typically investigated in animal models for microgravity. We recently evaluated bone microarchitecture in the femoral head in rapidly growing male Sprague Dawley rats subjected to a 4-day...

Resource Type:

Honors College Thesis

Full Text:

Sciences _____________________________________________________________________ Dawn Olson, Committee
Hypothalamic Leptin Gene Therapy Does Not Prevent Ovariectomy-Induced Bone Loss in Rats

Creator:

Jackson, Melanie A.

Abstract:

Post-menopausal women are at an increased risk for osteoporosis due to increased bone resorption associated with estrogen deficiency. Subcutaneous administration of leptin, a hormone produced primarily by adipocytes, attenuates bone loss in the ovariectomized (ovx) rat, an animal model for post-menopausal bone loss. Leptin has both direct peripheral and indirect...

Resource Type:

Honors College Thesis

Full Text:

Trevisiol, and Dawn Olson for lab camaraderie. All of you are an integral part of this project, and the
Effects of Estrogen Receptor Blockade on Skeletal Response to Alcohol in Ovariectomized Rats

Creator:

Wagner, Lindsay A.

Abstract:

Heavy alcohol consumption reduces peak bone mass in growing rodents and can lead to bone loss in both adult rats and humans. In contrast, moderate alcohol consumption appears to have a bone sparing effect in post-menopausal women. Alcohol has been reported to increase aromatase activity and influence estrogen receptor (ER)...

Resource Type:

Honors College Thesis

Full Text:

have been a success. I would also like to recognize Dawn Olson, Kenneth Philbrick, Bailey Lindenmaier