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Filtering by: Creator Pearse, William D. Remove constraint Creator: Pearse, William D. Committee Member Williams, David Remove constraint Committee Member: Williams, David Committee Member Dashwood, Roderick Remove constraint Committee Member: Dashwood, Roderick

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  • Prostate cancer prevention with broccoli : from cellular to human studies

    Creator:
    Clarke, John D.
    Abstract:
    Prostate cancer is the second leading cause of cancer related death in American men. Epidemiologic studies suggest that cruciferous vegetable intake may lower the risk for many cancers, including prostate and colon. Isothiocyanates (ITC) are phytochemicals derived from cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage that may...
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF John D. Clarke

  • Factors contributing to the formation of CC-->TT tandem mutations

    Creator:
    Skinner, Amy M.
    Abstract:
    The multistage model of carcinogenesis states that an accumulation of mutations in genes that are important for maintaining cellular homeostasis may lead to cancer. A specific type of mutation observed in particular types of cancer is the CC-->TT mutation found in the TP53 gene of patients with basal or squamous...
    Resource Type:
    Dissertation
    Full Text:
    chronic (24 hours) D-ala followed by UVC treatment……………………… 17. Mutational spectra induced by