Index Catalog // ScholarsArchive@OSU

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: Abstract approved: _____________________________________________________________________ William M

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Creator:: Taft, Oriane Williams
Abstract:: Understanding how wetland birds use habitat is pivotal to developing successful and beneficial conservation strategies. Although it has been an ardent topic in forest research for some time, how species interact with the spatial patterning of habitat across a landscape (i.e., landscape structure) has been more or less neglected in...
Resource Type:: Dissertation
Full Text:: (University of Nevada-Reno), Dennis Peters (NRCS), William Robbins (OSU), Peter Sanzenbacher, Jeff Steiner

Consequences of coumaphos and Varroa destructor on drone honey bee sperm quantity

Creator:: Delaney, Deborah Anne
Abstract:: The number of drones and genetic diversity among drones are essential components to a well mated queen. Varroa destructor preferentially parasitizes drone brood, and is thought to be responsible for the loss of feral populations that once provided additional drones for honey bee mating areas. It is necessary to use...
Resource Type:: Masters Thesis
Full Text:: my graduate committee. I am grateful to Dr. William Winner, former head of the Environmental

Studies on isoprenoid biosynthesis in Euglena gracilis

Creator:: Kim, Dojung
Abstract:: This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
Resource Type:: Dissertation
Full Text:: , the 2-C- methyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Creator:: Shenvi, Swapna V.
Abstract:: Glutathione (GSH) is the predominant low molecular weight thiol antioxidant in liver tissue. GSH plays an important role in maintaining the intracellular thiol redox ratio as well as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P ≤ 0.05) in hepatocellular GSH levels. Using young (2-4...
Resource Type:: Dissertation
Full Text:: like to thank my graduate committee members, Drs. William Baird, Balz Frei, Jeffrey Greenwood, and

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Creator:: Usenko, Crystal Y.
Abstract:: Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
Resource Type:: Masters Thesis

Molecular genetics and enzymology of secondary metabolite biosynthesis. I, Isolation of natural product biosynthesis gene clusters from symbiotic marine organisms. II, Enzymology of blasticidin S biosynthesis

Creator:: Grochowski, Laura L.
Abstract:: Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Resource Type:: Dissertation
Full Text:: -D- tryptophanyl-D--tyrosine) with a 12-carbon tetraketide that appears to be propionate- derived

Development and application of a new passive sampling device : the lipid-free tube (LFT) sampler

Creator:: Quarles, Lucas W.
Abstract:: Contaminants can exist in a wide range of states in aqueous environments, especially in surface waters. They can be freely dissolved or associated with dissolved or particulate organic matter depending on their chemical and physical characteristics. The freely dissolved fraction represents the most bioavailable fraction to an organism. These freely...
Resource Type:: Masters Thesis
Full Text:: Literature Cited 1. Schwarzenbach, R. P.; Gschwend, P. M.; Imboden, D. M., Environmental organic

Unraveling tissue regeneration using chemical genetics

Creator:: Mathew, Lijoy K.
Abstract:: The emerging field of regenerative medicine is mainly approached by two different aspects. First is the use of stem cell based models to generate a suite of differentiated cells for therapeutic applications and the alternative approach is to utilize the non-mammalian models that have the inherent capacity to regenerate their...
Resource Type:: Dissertation
Full Text:: , Koth CM, Buscher D, Kawakami Y, Itoh T, Raya RM, Sternik G, Tsai HJ, Rodriguez-Esteban C and Izpisua

The mechanism of interaction of the linker histone with DNA and nucleosomes

Creator:: Ellen, Thomas Patrick
Abstract:: This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
Resource Type:: Dissertation
Full Text:: presented on June 27.2003. APPROVED: Major Professor, Representing Biochemistry and Biophysics Chair of D

ScholarsArchive@OSU

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Consequences of coumaphos and Varroa destructor on drone honey bee sperm quantity

Studies on isoprenoid biosynthesis in Euglena gracilis

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Molecular genetics and enzymology of secondary metabolite biosynthesis. I, Isolation of natural product biosynthesis gene clusters from symbiotic marine organisms. II, Enzymology of blasticidin S biosynthesis

Development and application of a new passive sampling device : the lipid-free tube (LFT) sampler

Unraveling tissue regeneration using chemical genetics

The mechanism of interaction of the linker histone with DNA and nucleosomes

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