Index Catalog // ScholarsArchive@OSU

Interactions of Trichoderma reesei exo-acting cellulases with p-aminophenyl 1-thio-β-D-cellobioside

Creator:: Piyachomkwan, Kuakoon
Abstract:: Cellulolytic enzymes capable of efficiently degrading crystalline cellulose are a complex mixture of endo- (endoglucanases) and exo-acting (cellobiohydrolases) enzymes. One approach to separating these enzymes is affinity chromatography. A new ligand, p-aminophenyl l-thio-β-D-cellobioside (APTC), is introduced for this purpose. The property of APTC in affinity chromatography is demonstrated using Trichoderma...
Resource Type:: Dissertation
Full Text:: : Interaction of Trichoderma reesei Exo- Acting Cellulases With Immobilized p-Aminophenyl 1-Thio-^-D

Regulation of hepatic pyruvate carboxylase in 2,3,7,8-Tetrachlorodibenzo-p-dioxin treated C57BL/6J mice and their pair-fed controls

Creator:: Roy, Shukla
Resource Type:: Dissertation
Full Text:: - Tetrachlorodibenzo-p-dioxin Treated C57BL/6J Mice and their Pair-Fed Controls AN ABSTRACT OF THE THESIS OF Shukla

The mechanism of interaction of the linker histone with DNA and nucleosomes

Creator:: Ellen, Thomas Patrick
Abstract:: This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
Resource Type:: Dissertation
Full Text:: thanks to my graduate committee members, Dr. Robert Becker, Dr. Lyle Brown, and Dr. David Williams for

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Creator:: Choi, Jin-Young, 1964
Abstract:: Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to examine the role of hyperinflammation in TCDD-induced immunotoxicity. Previously we observed an increase in Mac-1⁺ cells in the spleen...
Resource Type:: Dissertation
Full Text:: in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) An Abstract of the

Electron molecule interactions of amino acids and peptides

Creator:: Figard, Benjamin J.
Abstract:: Electron-biomolecule interactions are a biologically relevant field of study because there are several ion fragmentation techniques that have come to the forefront in mass spectrometric analysis that involve the interaction of charged peptides and free electrons. By studying the electron energies that cause fragmentation in neutral amino acids, amino acid...
Resource Type:: Dissertation
Full Text:: peptide substance P. For peptides with carboxylic acids on the C-terminus, z-1 ions were observed

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: [a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

Creator:: Taur, Jan-Shiang
Abstract:: The goal of this dissertation is to investigate the interaction between cimetidine and dietary flavonoids using the Caco-2 cell transport model. It has been shown that flavonoids can change the bioavailability of pharmaceuticals, either by inhibiting metabolizing enzymes or inhibiting the drug efflux transporters. However, the effect of dietary flavonoids...
Resource Type:: Dissertation
Full Text:: cimetidine is mediated by a drug efflux pump, P-glycoprotein, of which dietary flavonoids can enhance the

A role for ceramide accumulation in age-related cardiac mitochondrial dysfunction

Creator:: Monette, Jeffrey S.
Abstract:: Ceramides are a group of lipids in the sphingolipid family that are potent cell signaling molecules. Elevations in ceramide levels above the norm generally lead to apoptosis. Evidence from in vitro studies suggests that accumulation of ceramides within mitochondria leads to dysfunction of the mitochondria. This includes inhibition of the...
Resource Type:: Dissertation
Full Text:: aging leads to a significant increase in total mitochondrial ceramides (32%, p < 0.03), with C16

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Creator:: Shenvi, Swapna V.
Abstract:: Glutathione (GSH) is the predominant low molecular weight thiol antioxidant in liver tissue. GSH plays an important role in maintaining the intracellular thiol redox ratio as well as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P ≤ 0.05) in hepatocellular GSH levels. Using young (2-4...
Resource Type:: Dissertation
Full Text:: as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P

Spatial and temporal variations of bioavailable polycyclic aromatic hydrocarbons in the lower Willamette River

Creator:: Sower, Gregory J.
Abstract:: Urban rivers with a history of industrial use can exhibit spatial and temporal variations in contaminant concentrations that may significantly affect risk evaluations and assessment of remediation efforts. To more effectively estimate human and ecological health risks, we evaluated the spatial and temporal distribution of polycyclic aromatic hydrocarbons (PAHs) in...
Resource Type:: Dissertation
Full Text:: Priority Pollutant PAHs 6 Literature Cited (1) Opperhulzen, A.; Volde, E. W.; Gobas, F. A. P. C

ScholarsArchive@OSU

Interactions of Trichoderma reesei exo-acting cellulases with p-aminophenyl 1-thio-β-D-cellobioside

Regulation of hepatic pyruvate carboxylase in 2,3,7,8-Tetrachlorodibenzo-p-dioxin treated C57BL/6J mice and their pair-fed controls

The mechanism of interaction of the linker histone with DNA and nucleosomes

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Electron molecule interactions of amino acids and peptides

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

A role for ceramide accumulation in age-related cardiac mitochondrial dysfunction

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Spatial and temporal variations of bioavailable polycyclic aromatic hydrocarbons in the lower Willamette River

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