Index Catalog // ScholarsArchive@OSU

Creator:: Figard, Benjamin J.
Abstract:: Electron-biomolecule interactions are a biologically relevant field of study because there are several ion fragmentation techniques that have come to the forefront in mass spectrometric analysis that involve the interaction of charged peptides and free electrons. By studying the electron energies that cause fragmentation in neutral amino acids, amino acid...
Resource Type:: Dissertation
Full Text:: peptide substance P. For peptides with carboxylic acids on the C-terminus, z-1 ions were observed

Creator:: Sandahl, Jason
Abstract:: The purpose of this work was to determine if environmentally-relevant concentrations of chlorpyrifos and copper, two commonly detected chemicals in Western surface waters, can negatively impact the biological health of salmonids. Both compounds are highly neurotoxic to fish, but each with distinct biological target sites and mechanisms of action. We...
Resource Type:: Dissertation
Full Text:: support provided by David Baldwin and Jana Labenia, much of this work would not have been possible. I

Creator:: Larsen, Christine A.
Abstract:: Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
Resource Type:: Dissertation
Full Text:: as follows: sema domain (S), cysteine-rich domain (C), immunoglobulin domains (Ig1-4

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: kinase C pmol/mg picomole of PAH-DNA adducts/milligram of DNA PMSF phenylmethylsulfonylfluoride

Creator:: Taft, Oriane Williams
Abstract:: Understanding how wetland birds use habitat is pivotal to developing successful and beneficial conservation strategies. Although it has been an ardent topic in forest research for some time, how species interact with the spatial patterning of habitat across a landscape (i.e., landscape structure) has been more or less neglected in...
Resource Type:: Dissertation
Full Text:: ) class 2: wet, >50% vegetation; C) class 3: dry, <50% vegetation; and D) class : dry, >50% vegetation. 49

Creator:: Ellen, Thomas Patrick
Abstract:: This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
Resource Type:: Dissertation
Full Text:: ........................................................................................................ 5 C. The Location of the Linker Histone on the Nucleosome ....................................23 D

Creator:: Clarke, John D.
Abstract:: Prostate cancer is the second leading cause of cancer related death in American men. Epidemiologic studies suggest that cruciferous vegetable intake may lower the risk for many cancers, including prostate and colon. Isothiocyanates (ITC) are phytochemicals derived from cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage that may...
Resource Type:: Dissertation
Full Text:: , cyclin A, and c-myc (23). A G1/S block in LnCap and DU145 prostate cells has also been reported at

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