Index Catalog // ScholarsArchive@OSU

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Creator:: Núñez, Oliva
Resource Type:: Masters Thesis
Full Text:: members of my graduate comittee Dr. Christophen Bayne, Dr. David Hinton, and Dr. David Williams, for

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: concerning enzyme kinetics and Dr. David Williams for pointing out the flavin binding motif in the N

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

Creator:: Taur, Jan-Shiang
Abstract:: The goal of this dissertation is to investigate the interaction between cimetidine and dietary flavonoids using the Caco-2 cell transport model. It has been shown that flavonoids can change the bioavailability of pharmaceuticals, either by inhibiting metabolizing enzymes or inhibiting the drug efflux transporters. However, the effect of dietary flavonoids...
Resource Type:: Dissertation
Full Text:: Ayres, Dr. Mark Cliristiansen, Dr. David Birkes, and Dr. David Williams, for their precious suggestion

Unraveling tissue regeneration using chemical genetics

Creator:: Mathew, Lijoy K.
Abstract:: The emerging field of regenerative medicine is mainly approached by two different aspects. First is the use of stem cell based models to generate a suite of differentiated cells for therapeutic applications and the alternative approach is to utilize the non-mammalian models that have the inherent capacity to regenerate their...
Resource Type:: Dissertation
Full Text:: to thank all my committee members, namely, Dr. David Williams, Dr. Nancy Kerkvliet, Dr. Mark Leid

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Creator:: Taft, Oriane Williams
Abstract:: Understanding how wetland birds use habitat is pivotal to developing successful and beneficial conservation strategies. Although it has been an ardent topic in forest research for some time, how species interact with the spatial patterning of habitat across a landscape (i.e., landscape structure) has been more or less neglected in...
Resource Type:: Dissertation
Full Text:: David Williams for their expertise, support and encouragement. Gay has been pivotal in encouraging me

Biochemical and physiological indicators of behavioral impairment in salmonids exposed to chlorpyrifos and copper

Creator:: Sandahl, Jason
Abstract:: The purpose of this work was to determine if environmentally-relevant concentrations of chlorpyrifos and copper, two commonly detected chemicals in Western surface waters, can negatively impact the biological health of salmonids. Both compounds are highly neurotoxic to fish, but each with distinct biological target sites and mechanisms of action. We...
Resource Type:: Dissertation
Full Text:: support provided by David Baldwin and Jana Labenia, much of this work would not have been possible. I

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:: Scheri, Richard C.
Abstract:: Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...
Resource Type:: Dissertation
Full Text:: . David Williams and Dr. Mark Harmon. Many thanks to Dr. Dave Williams lab and especially to Beth

Utilization of lignocellulosic polysaccharides

Creator:: Fenske, John J.
Abstract:: Lignocellulosic biomass represents a vast supply of fermentable carbohydrates and functional aromatic compounds. Conversion of lignocellulosics to ethanol and other useful products would be of widespread economical and environmental benefit. Better understanding of the behavior of different lignicellulosic feedstocks in fermentation protocols as well as catalytic activities involved in lignocellulosic...
Resource Type:: Dissertation
Full Text:: thank my committee members, Professors Alan Bakalinsky, John Bolte, David Williams and Bill Braunworth

Hypermutagenic induction of mitotic recombination by ionizing radiation in Mlhl null mouse cells

Creator:: Wang, Qi
Abstract:: Mitotic recombination is a common autosomal mutation in mammalian cells involving crossover events between homologous chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous deficiency, and thus often represents the second step in tumor suppressor gene inactivation. In this study I examined the...
Resource Type:: Masters Thesis
Full Text:: . Andrew Buermeyer, Prof. David Williams and Prof. Jeffrey Stone for their wise counsel and support. I

Regulation of NMDA-type glutamate receptors and MDR1 by two members of the EF-hand protein family

Creator:: Bajaj, Gaurav
Abstract:: EF-hand proteins are a conserved family of proteins that are modulated by divalent cations and regulate diverse cellular activities. In the present study we characterized the molecular determinants of myosin regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Myosin RLC is an EF-hand protein...
Resource Type:: Dissertation
Full Text:: , Dr. Kathy Magnusson, and Dr. David Williams for their guidance and encouragement. I would also

ScholarsArchive@OSU

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

Unraveling tissue regeneration using chemical genetics

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Biochemical and physiological indicators of behavioral impairment in salmonids exposed to chlorpyrifos and copper

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Utilization of lignocellulosic polysaccharides

Hypermutagenic induction of mitotic recombination by ionizing radiation in Mlhl null mouse cells

Regulation of NMDA-type glutamate receptors and MDR1 by two members of the EF-hand protein family

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