Index Catalog // ScholarsArchive@OSU

Molecular genetics and enzymology of secondary metabolite biosynthesis. I, Isolation of natural product biosynthesis gene clusters from symbiotic marine organisms. II, Enzymology of blasticidin S biosynthesis

Creator:: Grochowski, Laura L.
Abstract:: Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Resource Type:: Dissertation
Full Text:: Enzymology of Secondary Metabolite Biosynthesis: I. Isolation of Natural Product Biosynthesis Gene Clusters

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Creator:: Choi, Jin-Young, 1964
Abstract:: Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to examine the role of hyperinflammation in TCDD-induced immunotoxicity. Previously we observed an increase in Mac-1⁺ cells in the spleen...
Resource Type:: Dissertation
Full Text:: Department of Environmental and Molecular Toxicology Dean of duate School Redacted for Privacy I

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Creator:: Núñez, Oliva
Resource Type:: Masters Thesis
Full Text:: ₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: sincere gratitude. Foremost, I would like to extend my warmest appreciation to Professor William

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: Abstract approved: _____________________________________________________________________ William M

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Creator:: Taft, Oriane Williams
Abstract:: Understanding how wetland birds use habitat is pivotal to developing successful and beneficial conservation strategies. Although it has been an ardent topic in forest research for some time, how species interact with the spatial patterning of habitat across a landscape (i.e., landscape structure) has been more or less neglected in...
Resource Type:: Dissertation
Full Text:: local and landscape scale, I assessed the: 1) historical (circa 1840) nature and waterbird use of

Consequences of coumaphos and Varroa destructor on drone honey bee sperm quantity

Creator:: Delaney, Deborah Anne
Abstract:: The number of drones and genetic diversity among drones are essential components to a well mated queen. Varroa destructor preferentially parasitizes drone brood, and is thought to be responsible for the loss of feral populations that once provided additional drones for honey bee mating areas. It is necessary to use...
Resource Type:: Masters Thesis
Full Text:: my graduate committee. I am grateful to Dr. William Winner, former head of the Environmental

Spatial and temporal variations of bioavailable polycyclic aromatic hydrocarbons in the lower Willamette River

Creator:: Sower, Gregory J.
Abstract:: Urban rivers with a history of industrial use can exhibit spatial and temporal variations in contaminant concentrations that may significantly affect risk evaluations and assessment of remediation efforts. To more effectively estimate human and ecological health risks, we evaluated the spatial and temporal distribution of polycyclic aromatic hydrocarbons (PAHs) in...
Resource Type:: Dissertation
Full Text:: Dean of the Graduate School I understand that my dissertation will

Interactions of Trichoderma reesei exo-acting cellulases with p-aminophenyl 1-thio-β-D-cellobioside

Creator:: Piyachomkwan, Kuakoon
Abstract:: Cellulolytic enzymes capable of efficiently degrading crystalline cellulose are a complex mixture of endo- (endoglucanases) and exo-acting (cellobiohydrolases) enzymes. One approach to separating these enzymes is affinity chromatography. A new ligand, p-aminophenyl l-thio-β-D-cellobioside (APTC), is introduced for this purpose. The property of APTC in affinity chromatography is demonstrated using Trichoderma...
Resource Type:: Dissertation
Full Text:: classified into two classes, based on their hydrolytic specificities. Class I enzymes preferentially

Studies on isoprenoid biosynthesis in Euglena gracilis

Creator:: Kim, Dojung
Abstract:: This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
Resource Type:: Dissertation
Full Text:: ( re'senting Pharmacy Dean of the clollecie of Pha Dean of t(i Giaduate School I understand that my

ScholarsArchive@OSU

Molecular genetics and enzymology of secondary metabolite biosynthesis. I, Isolation of natural product biosynthesis gene clusters from symbiotic marine organisms. II, Enzymology of blasticidin S biosynthesis

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Consequences of coumaphos and Varroa destructor on drone honey bee sperm quantity

Spatial and temporal variations of bioavailable polycyclic aromatic hydrocarbons in the lower Willamette River

Interactions of Trichoderma reesei exo-acting cellulases with p-aminophenyl 1-thio-β-D-cellobioside

Studies on isoprenoid biosynthesis in Euglena gracilis

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search