Index Catalog // ScholarsArchive@OSU

Creator:: Zhang, Jinying
Abstract:: Quinolinate (QUIN) is an endogenous neurotoxic product of the kynurenine pathway of tryptophan metabolism. Quinolinate is a selective agonist of the NMDA family of glutamate receptors and, as such, may play a role in the pathology of a number of major central nervous system (CNS) disorders. These include both chronic...
Resource Type:: Masters Thesis
Full Text:: . 300 W Cr.1 i POO 1 J''''a1000 - el 0 -7 -6 -5 -.! -3 -2 LOG GLU (M) Figure 6

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: -1 245. (b) Verdier-Pinard, P.; Sitachitta, N.; Rossi, J. V.; Sackett, D. L.; Gerwick, W. H.; Hamel

Creator:: Kim, Dojung
Abstract:: This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
Resource Type:: Dissertation
Full Text:: thank my major Professor, Philip J. Proteau, for his support, guidance, and patience throughout my

Creator:: Nannini, Christopher J.
Abstract:: Marine organisms produce a variety of secondary metabolites for defense, communication, and reproduction. While these uses are essential for the organisms' survival, marine natural products have demonstrated their value to human society as well. Asian countries used algae for centuries to treat or prevent illnesses as wide-ranging as cough, gout,...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Christopher J. Nannini for the

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: - +H3N ..7.__&:)L..ir0 N FL j 0 R £ R FMN R Figure 1.7: Reactions catalyzed by NRPS tailoring domains

Creator:: Geng, Yu
Abstract:: Wood-plastic composites (WPCs) are one of the fastest-growing sectors of the wood composites industry. However, the strengths of WPCs are typically low because of the poor interfacial adhesion between hydrophilic wood and hydrophobic thermoplastics. A compatibilizer that can form bridges between wood and plastics is required to give WPCs desirable...
Resource Type:: Dissertation
Full Text:: was first used as a wood adhesive for particleboard by H.-J. Deppe in 1971 (Frisch and Rumao 1983

Creator:: Andrianasolo, Eric Hajaniriana
Abstract:: This thesis is an investigation of the natural products deriving from marine algae and cyanobacteria and has resulted in the discovery of eleven new secondary metabolites. The structure elucidations of these new molecules were performed using a variety of spectroscopic techniques. Four new macrolides were isolated and characterized from the...
Resource Type:: Dissertation
Full Text:: HMBC spectrum (optimized for J = 8Hz) of ankaraholide A (1) in CD3OD

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