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Filtering by: Creator Bograd, Steven J. Contributor Brian Dolan Degree Name Honors Bachelor of Science (H.B.S.)

Evaluation of a Monoclonal Antibody for Studying MHC Class I Antigen Presentation In-Vitro

Creator:

VanderHoek, Eden N.

Abstract:

Human epidermal growth factor receptor 2 (HER2), a member of the receptor tyrosine kinase (RTK) family, is frequently dysregulated in a variety of cancers. Overexpression of the receptor leads to increased cell proliferation and resistance to cell death due to downstream signaling effects. Proteasomal degradation of HER2 results in the...

Resource Type:

Honors College Thesis

Full Text:

. Burstein, Harold J. “The Distinctive Nature of HER2-Positive Breast Cancers.” New England Journal of