Search Constraints

Start Over
Filtering by: Has journal Virus Genes Remove constraint Has journal: Virus Genes Contributor Damnernsawad, Alisa Remove constraint Contributor: Damnernsawad, Alisa License Attribution 4.0 (CC BY 4.0) Remove constraint License: Attribution 4.0 (CC BY 4.0)

Search Results

  • Role of MEK Mutations in Trametinib Resistant Acute Myeloid Leukemia Cells

    Creator:
    Beer, Sofia R.
    Abstract:
    Acute myeloid leukemia (AML) is a blood malignancy characterized by a differentiation and proliferation defect of myeloid progenitors leading to accumulation of myeloid blasts. It is one of the most common leukemias in adults. Trametinib (Mekinist) is a small molecule inhibitor that targets MEK1 (MAP2K1) and MEK2 (MAPK2K2). It has...
    Resource Type:
    Honors College Thesis
    Full Text:
    inserted gene (8). Any cell that still expresses ccdB dies, while the ones with the inserted genes