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Filtering by: Creator Kent, Adam J. R. Contributor Danelishvili, Lia Degree Name Master of Science (M.S.)

Exploration of the Phage Adsorption Mechanism in Mycobacterium abscessus Toward Improving the Efficacy of Current Antibiotics

Creator:

Gorzynski, Mylène

Abstract:

Background: Mycobacterium abscessus (MAB) is a rapidly growing opportunistic pathogen that causes infections in immunocompromised patients. The highly impermeable cell wall and surface transport systems are major contributing factors to MAB intrinsic resistance, influencing the efficacy of bactericidal antibiotics. Phages are promising alternatives to antibiotics and have been used in...

Resource Type:

Masters Thesis

Full Text:

. Michael Kent, and Dr. Jeff Bethel, for giving their time and providing advice on courses and my research
Identification of Mycobacterium smegmatis Surface Proteins for Stimulation of Anti-Mycobacterial Killing Activity of Macrophages

Creator:

Islam, Sabrina

Abstract:

Mycobacterium avium subspecies hominissuis (M. avium) is a ubiquitous, acid-fast organism found in water and soil. This opportunistic pathogen is a common causative of pulmonary diseases in immunocompromised individuals and prevalent infection in HIV/AIDS patients. As a primary defense response against infection, immune cells such as macrophages phagocytize M. avium...

Resource Type:

Masters Thesis