Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Cooper, Ranessa L. Contributor Danelishvili, Lia Language English [eng]

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:

Phillips, Ida L.

Abstract:

Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...

Resource Type:

Dissertation

Full Text:

ABSTRACT OF THE DISSERTATION OF Ida L. Phillips for the degree of Doctor of Philosophy in Comparative
Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Creator:

Chiplunkar, Sanket S.

Abstract:

Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...

Resource Type:

Masters Thesis

Full Text:

% (v/v) glycerol 11µl of 1 M CuSO4 100µl of 500mg/L ferric ammonium citrate 117.4µl of 1 M ZnCl2