Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Daley, Bryon A. Contributor Danelishvili, Lia

Quantitative Analysis of Mycobacterium avium subsp. hominissuis and Mycobacterium abscessus subs. abscessus Proteome in Response to Antibiotics and During Exposure to Different Environmental Conditions

Creator:

Rojony, Rajoana

Abstract:

M. avium subsp. hominissuis (MAH) and M. abscessus subsp. abscessus (MAB) both belong to the clinically important non-tuberculous mycobacterial (NTM) group that infect immunocompromised patients with AIDS and individuals with underlining lung conditions such as bronchiectasis or cystic fibrosis. The main challenge of treating MAH and MAB patients is an...

Resource Type:

Masters Thesis

Full Text:

pathogens with multiple compounds even at the bactericidal concentrations. As a result, MAV requires
Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:

Joseph, Jayanthi J.

Abstract:

To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...

Resource Type:

Dissertation

Full Text:

: _____________________________________________________________________ Luiz E. Bermudez Mycobacterium avium subsp. hominissuis (M. avium) is a