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Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis
Full Text:: and catalase (OADC, Hardy Diagnostics, Santa Maria, CA) at 37º C, until mid-log phase (which is 7-8

Creator:: Rojony, Rajoana
Abstract:: M. avium subsp. hominissuis (MAH) and M. abscessus subsp. abscessus (MAB) both belong to the clinically important non-tuberculous mycobacterial (NTM) group that infect immunocompromised patients with AIDS and individuals with underlining lung conditions such as bronchiectasis or cystic fibrosis. The main challenge of treating MAH and MAB patients is an...
Resource Type:: Masters Thesis
Full Text:: . Matthew Martin and Pankaj Jaiswal analyzed proteomic data. Anaamika Campeau, Jacob M. Wozniak and David

Creator:: Gorzynski, Mylène
Abstract:: Background: Mycobacterium abscessus (MAB) is a rapidly growing opportunistic pathogen that causes infections in immunocompromised patients. The highly impermeable cell wall and surface transport systems are major contributing factors to MAB intrinsic resistance, influencing the efficacy of bactericidal antibiotics. Phages are promising alternatives to antibiotics and have been used in...
Resource Type:: Masters Thesis
Full Text:: several antibiotic- resistant infections other than mycobacteria, such as C. difficile, P. aeruginosa

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation
Full Text:: inflammasome leads to cell death by pyroptosis or necroptosis (Swanson et al., 2019, p. 3; Wong & Jacobs Jr

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