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Filtering by: Creator Katz, Daniel Louis Contributor Danelishvili, Lia

Mycobacterium abscessus genetic determinants associated with intrinsic resistance to antibiotics

Creator:

Gorzynski, Mylene

Abstract:

M. abscessus subsp. abscessus is a nontuberculous mycobacterium causing pulmonary infections in immunocompromised patients. The treatment of MAB infections is challenging due to its natural resistance to most antibiotics. To identify MAB genetic factors that are involved in mechanisms of the antibiotic tolerance, we screened the library of 2,000 gene...

Resource Type:

Honors College Thesis

Full Text:

with 20 ng/mL of Phorbol 12-myristate 13-acetate (PMA; Sigma-Aldrich, Saint Louis, MO, USA
Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:

Phillips, Ida L.

Abstract:

Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...

Resource Type:

Dissertation