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Filtering by: Creator Lange, C. B. Contributor Freitag, Michael Non-Academic Affiliation Oregon State University. Honors College

Generation of expression plasmids to study the function of the PRC2 subunit Suz12 in Fusarium graminearum

Creator:

Park, Catherine

Abstract:

The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...

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Honors College Thesis

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) These plasmids were used to generate fragments containing only a portion of the hph gene (b, c) that can
The role of the putative transcription factor DIS10 in PRC2-mediated gene silencing

Creator:

Jackson, Kendra K.

Abstract:

PRC2 (Polycomb Repressive Complex 2) mediated gene silencing plays an important role in cell differentiation, stem cell plasticity, and tumor suppression. In fungi, it is also involved in pathogenicity. The catalytic subunit, KMT6, trimethylates lysine 27 on histone h3 (H3K27me3) at loci targeted for silencing. In animals, PRC1 and PRC2...

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Honors College Thesis

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UCSF chimera [11]. (C) Single display of DIS10 FAR1 domain and (D) WRKY4 WRKY domain. A B
A Panel of Histone H3 Mutations to Investigate Centromere Maintenance and Gene Silencing

Creator:

Geisler, Mark S.

Abstract:

Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...

Resource Type:

Honors College Thesis

Full Text:

with the desired mutation to hH3 are synthesized by PCR. The plasmids pSF6 (b) and pRG9 (c) were used

ScholarsArchive@OSU

Generation of expression plasmids to study the function of the PRC2 subunit Suz12 in Fusarium graminearum

The role of the putative transcription factor DIS10 in PRC2-mediated gene silencing

A Panel of Histone H3 Mutations to Investigate Centromere Maintenance and Gene Silencing

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