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Filtering by: Creator Kellogg, Royal S. Remove constraint Creator: Kellogg, Royal S. Contributor Jiang, Yuan Remove constraint Contributor: Jiang, Yuan Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • Microbial Network Recovery by Compositional Graphical Lasso Under Additive Log-Ratio Transformation

    Creator:
    Tian, Chuan
    Abstract:
    The interactions between microbial taxa have been under great research interest in the sci- ence community given the microbiome data deluge. Several methods have been proposed to model and estimate the conditional dependency between microbial taxa for their interac- tions, in order to eliminate spurious correlation detections. However, these methods...
    Resource Type:
    Dissertation
    Full Text:
    , and to have him as a friend that I look up to. Secondly, my great appreciation of the two co-P.I.’s

  • Regularization-Based Data Integration and Its Application to Genome-Wide Association Studies

    Creator:
    Li, Kai
    Abstract:
    In genome-wide association studies, it is often challenging to have consistent findings from independent studies. This "lack of reproducibility" issue is partially caused by the relatively small sample size compared to the number of genetic markers in every single study. Therefore, researchers have developed statistical methods to integrate multiple studies...
    Resource Type:
    Dissertation
    Full Text:
    coefficients for the eight relevant groups: α’s from the first dataset and β’s from the second dataset

  • Impacts of microbial chemical interactions on marine plankton physiology

    Creator:
    Moore, Eric R.
    Abstract:
    The bioavailability of chemical compounds in the marine environment fundamentally influences the growth and physiology of microorganisms. Organic and inorganic chemicals that are produced by some marine plankton can be consumed by other plankton for energy production, growth, or to initiate essential physiological processes. Cultures of the diatom Thalassiosira pseudonana,...
    Resource Type:
    Dissertation