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Filtering by: Contributor Jiang, Yuan Remove constraint Contributor: Jiang, Yuan Language English [eng] Remove constraint Language: English [eng] Resource Type Dissertation Remove constraint Resource Type: Dissertation

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Regularization-Based Data Integration and Its Application to Genome-Wide Association Studies

Creator:

Li, Kai

Abstract:

In genome-wide association studies, it is often challenging to have consistent findings from independent studies. This "lack of reproducibility" issue is partially caused by the relatively small sample size compared to the number of genetic markers in every single study. Therefore, researchers have developed statistical methods to integrate multiple studies...

Resource Type:

Dissertation
Advanced Mass Spectrometry Techniques for Characterizations of Proteome and Lipidome Profiles of Osteosarcoma Cells

Creator:

Song, Zifeng

Abstract:

Mass Spectrometry has emerged as an analytical core technique in omics sciences, in particularly mass spectrometry has advanced the fields of proteomics, metabolomics and lipidomics in recent years. Mass spectrometric techniques have enabled the characterization and determination of abundance levels of a wide range of biomolecules at molecular and system-wide...

Resource Type:

Dissertation
Impacts of microbial chemical interactions on marine plankton physiology

Creator:

Moore, Eric R.

Abstract:

The bioavailability of chemical compounds in the marine environment fundamentally influences the growth and physiology of microorganisms. Organic and inorganic chemicals that are produced by some marine plankton can be consumed by other plankton for energy production, growth, or to initiate essential physiological processes. Cultures of the diatom Thalassiosira pseudonana,...

Resource Type:

Dissertation
Microbial Network Recovery by Compositional Graphical Lasso Under Additive Log-Ratio Transformation

Creator:

Tian, Chuan

Abstract:

The interactions between microbial taxa have been under great research interest in the sci- ence community given the microbiome data deluge. Several methods have been proposed to model and estimate the conditional dependency between microbial taxa for their interac- tions, in order to eliminate spurious correlation detections. However, these methods...

Resource Type:

Dissertation

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Academic Affiliation

Statistics2
Chemistry1
Microbiology1

Advisor

Jiang, Yuan2
Halsey, Kimberly1
Maier, Claudia1

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 2018 to 2021

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Committee Member

Chang, Jeff1
Charlotte, Wickham1
Giovannoni, Stephen1
Gombart, Adrian1
Harold, Bae1
more Committee Members »

Creator

Li, Kai1
Moore, Eric R.1
Song, Zifeng1
Tian, Chuan1

Contributor

Jiang, Yuan[remove]4
Bracha, Shay1
Bullington, Brianna1
Chang, Jeff1
Davis, Ed1
more Contributors »

Date

Date range begin – Date range end

Current results range from 2017 to 2020

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Decade

2020-20291
2010-20193

Degree Field

Statistics2
Chemistry1
Microbiology1

Degree Level

Doctoral4

Degree Name

Doctor of Philosophy (Ph.D.)4

Language

English [eng][remove]4

License

All rights reserved4

Peer Reviewed

No3

Resource Type

Dissertation[remove]4

Rights Statement

In Copyright4

Subject

Integrative analysis1
Meta-analysis1
Regularization1
Statistics1

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