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Filtering by: Creator Moore, Paul Harris Contributor Taratula, Oleh Degree Field Pharmaceutical Sciences

A Nanoparticle Mediated Gene Silencing Approach for the Treatment of Metastatic Ovarian Cancer

Creator:

Schumann, Canan B.

Abstract:

Ovarian cancer, “the silent killer,” is one of the deadliest gynecological diseases due to delayed diagnosis, leading to a heavily disseminated and aggressive metastatic cancer. Therapeutic options are limited at stages III-IV of ovarian cancer, in which debulking surgery and cytotoxic chemotherapy remain the mainstays of intervention. However, these therapeutic...

Resource Type:

Dissertation

Full Text:

, MRCP, Steven W. Remmenga, MD, Paul Sabbatini, MD, Russell J. Schilder, MD, Julian C. Schink, MD
Identification of Cervical Cancer Key Regulators using Network Biology Approach

Creator:

Vyshenska, Dariia

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause of the disease. Currently available treatment methods are limited and emphasize the need for discovery of new therapies that improve patient outcome. Chromosomal amplifications have been identified as a source of...

Resource Type:

Dissertation