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Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis
Full Text:: and catalase (OADC, Hardy Diagnostics, Santa Maria, CA) at 37º C, until mid-log phase (which is 7-8

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation
Full Text:: by T cells, are instrumental in granuloma formation during mycobacterial infection (Smith et al

Creator:: Islam, Sabrina
Abstract:: Mycobacterium avium subspecies hominissuis (M. avium) is a ubiquitous, acid-fast organism found in water and soil. This opportunistic pathogen is a common causative of pulmonary diseases in immunocompromised individuals and prevalent infection in HIV/AIDS patients. As a primary defense response against infection, immune cells such as macrophages phagocytize M. avium...
Resource Type:: Masters Thesis
Full Text:: ). Autophagy can be regulated with PRR, scavenger receptors, c-type lectin receptors, and TLR activation. NF

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation
Full Text:: specificity of 96% (Bower et al.) (Smith et al.). Full-thickness biopsies of the liver, intestines, and

Creator:: Rojony, Rajoana
Abstract:: M. avium subsp. hominissuis (MAH) and M. abscessus subsp. abscessus (MAB) both belong to the clinically important non-tuberculous mycobacterial (NTM) group that infect immunocompromised patients with AIDS and individuals with underlining lung conditions such as bronchiectasis or cystic fibrosis. The main challenge of treating MAH and MAB patients is an...
Resource Type:: Masters Thesis
Full Text:: . 6 References: [1] N. Rastogi, E. Legrand, and C. Sola, “The mycobacteria : an

Creator:: Gorzynski, Mylène
Abstract:: Background: Mycobacterium abscessus (MAB) is a rapidly growing opportunistic pathogen that causes infections in immunocompromised patients. The highly impermeable cell wall and surface transport systems are major contributing factors to MAB intrinsic resistance, influencing the efficacy of bactericidal antibiotics. Phages are promising alternatives to antibiotics and have been used in...
Resource Type:: Masters Thesis
Full Text:: several antibiotic- resistant infections other than mycobacteria, such as C. difficile, P. aeruginosa

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