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Filtering by: Has journal Biology & Philosophy Remove constraint Has journal: Biology & Philosophy Creator Al Fageeh, Mohamed B. Remove constraint Creator: Al Fageeh, Mohamed B. Resource Type Masters Thesis Remove constraint Resource Type: Masters Thesis

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  • Functional analysis of novel β-catenin mutants

    Creator:
    Al-Fageeh, Mohamed B.
    Abstract:
    β-catenin is a multi functional protein that is involved in cell-cell adhesion and cell signaling. In non-stimulated cells, β-catenin is tightly down-regulated by GSK-3β-dependent phosphorylation at Ser and Thr residues, followed by rapid ubiquitination and proteasomal degradation. It is well established that mutations within the regulatory GSK-3β region lead to...
    Resource Type:
    Masters Thesis