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Filtering by: Creator Mulligan, Daniel M. Remove constraint Creator: Mulligan, Daniel M. Creator Almabruk, Khaled Husain G. Remove constraint Creator: Almabruk, Khaled Husain G. Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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  • Development and testing of novel anti-tubercular drugs

    Creator:
    Almabruk, Khaled Husain G.
    Abstract:
    Tuberculoѕiѕ (TB) iѕ a number one killer among treatable infectious diseases. It is caused by the pathogenic bacterium Mycobacterium tuberculoѕiѕ that primarily affects the lungѕ. It infects one third of the world population and kills approximately 2 million people each year (based on WHO report). Drug-reѕiѕtant TB haѕ become a...
    Resource Type:
    Masters Thesis
    Full Text:
    vertebrates. In M. tuberculosis, trehalose-6,6'-dimycolate (TDM) and trehalose-6-monomycolate (TMM) as well

  • Development of Novel Agents to Combat Tuberculosis and Malaria

    Creator:
    Almabruk, Khaled Husain G.
    Abstract:
    Despite the advance of biomedical science, infectious diseases remain one of the number one killers in the world. They claim the lives of millions of people annually, particularly in underdeveloped and developing countries. In fact, more than 32% of the health burden in Africa is caused by infectious diseases, e.g.,...
    Resource Type:
    Dissertation
    Full Text:
    resistant strains of M. tuberculosis in recent years has rendered some of the first-line anti-TB drugs