Search Constraints

Start Over
Filtering by: Subject Ketoconazole -- Mechanism of action Remove constraint Subject: Ketoconazole -- Mechanism of action Creator Amantana, Adams Remove constraint Creator: Amantana, Adams

Search Results

  • Characterization of rodent selenoprotein W promoter

    Creator:
    Amantana, Adams
    Abstract:
    Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
    Resource Type:
    Dissertation
    Full Text:
    MRE sequence are critical to the metal induction of SeW promoter. The mechanism underlying this