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Chang, Fu-Lung
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Amedei, Amedeo
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- Creator:
- Ochieng, Josiah, Nangami, Gladys N., Ogunkua, Olugbemiga, Miousse, Isabelle R., Koturbash, Igor, Odero-Marah, Valerie, McCawley, Lisa J., Nangia-Makker, Pratima, Ahmed, Nuzhat, Luqmani, Yunus, Chen, Zhenbang, Papagerakis, Silvana, Wolf, Gregory T., Dong, Chenfang, Zhou, Binhua P., Brown, Dustin G., Colacci, Annamaria, Hamid, Roslida A., Mondello, Chiara, Raju, Jayadev, Ryan, Elizabeth P., Woodrick, Jordan, Scovassi, A. Ivana, Singh, Neetu, Vaccari, Monica, Roy, Rabindra, Forte, Stefano, Memeo, Lorenzo, Salem, Hosni K., Amedei, Amedeo, Al-Temaimi, Rabeah, Al-Mulla, Fahd, Bisson, William H., and Eltom, Sakina E.
- Abstract:
- The purpose of this review is to stimulate new ideas regarding low-dose environmental mixtures and carcinogens and their potential to promote invasion and metastasis. Whereas a number of chapters in this review are devoted to the role of lowdose environmental mixtures and carcinogens in the promotion of invasion and metastasis...
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- ‘Carcinogenesis’ was the realization that cigarette smoke contains many carcinogens that initiate lung cancer
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- Creator:
- Kravchenko, Julia, Corsini, Emanuela, Williams, Marc A., Bisson, William H., Decker, William, Manjili, H. Masoud, Otsuki, Takemi, Sing, Neetu, Al-Mulla, Faha, Al-Temaimi, Rabeah, Amedei, Amedeo, Colacci, Anna Maria, Vaccari, Monica, Mondello, Chiara, Scovassi, A. Ivana, Raju, Jayadev, Hamid, Roslida A., Memeo, Lorenzo, Forte, Stefano, Roy, Rabindra, Woodrick, Jordan, Salem, Hosni K., Ryan, Elizabeth P., Brown, Dustin G., Bisson, william H., Lowe, Leroy, and Lyerly, H. Kim
- Abstract:
- An increasing number of studies suggest an important role of host immunity as a barrier to tumor formation and progression. Complex mechanisms and multiple pathways are involved in evading innate and adaptive immune responses, with a broad spectrum of chemicals displaying the potential to adversely influence immunosurveillance. The evaluation of...
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- of lung cancer after adjusting for smoking status) (23,24). An important role of T cells in
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- Creator:
- Langie, Sabine A. S., Koppen, Gudrun, Desaulniers, Daniel, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Azqueta, Amaya, Bisson, William H., Brown, Dustin, Brunborg, Gunnar, Charles, Amelia K., Chen, Tao, Colacci, Annamaria, Darroudi, Firouz, Forte, Stefano, Gonzalez, Laetitia, Hamid, Roslida A., Knudsen, Lisbeth E., Leyns, Luc, Lopez de Cerain Salsamendi, Adela, Memeo, Lorenzo, Mondello, Chiara, Mothersill, Carmel, Olsen, Ann-Karin, Pavanello, Sofia, Raju, Jayadev, Rojas, Emilio, Roy, Rabindra, Ryan, Elizabeth, Ostrosky-Wegman, Patricia, Salem, Hosni K., Scovassi, A. Ivana, Singh, Neetu, Vaccari, Monica, Van Schooten, Frederik J., Valverde, Mahara, Woodrick, Jordan, Zhang, Luoping, van Larebeke, Nik, Kirsch-Volders, Micheline, and Collins, Andrew R.
- Abstract:
- Genome instability is a prerequisite for the development of cancer. It occurs when genome maintenance systems fail to safeguard the genome’s integrity, whether as a consequence of inherited defects or induced via exposure to environmental agents (chemicals, biological agents and radiation). Thus, genome instability can be defined as an enhanced...
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- induction and cancer development is the increased incidence of cancers of the lung, skin, bladder and
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- Creator:
- Casey, Stephanie C., Vaccari, Monica, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Barcellos-Hoff, Mary Helen, Brown, Dustin G., Chapellier, Marion, Christopher, Joseph, Curran, Colleen S., Forte, Stefano, Hamid, Roslida A., Heneberg, Petr, Koch, Daniel C., Krishnakumar, P. K., Laconi, Ezio, Maguer-Satta, Veronique, Marongiu, Fabio, Memeo, Lorenzo, Mondello, Chiara, Raju, Jayadev, Roman, Jesse, Roy, Rabindra, Ryan, Elizabeth P., Ryeom, Sandra, Salem, Hosni K., Scovassi, A. Ivana, Singh, Neetu, Soucek, Laura, Vermeulen, Louis, Whitfield, Jonathan R., Woodrick, Jordan, Colacci, Annamaria, Bisson, William H., and Felsher, Dean W.
- Abstract:
- Potentially carcinogenic compounds may cause cancer through direct DNA damage or through indirect cellular or physiological effects. To study possible carcinogens, the fields of endocrinology, genetics, epigenetics, medicine, environmental health, toxicology, pharmacology and oncology must be considered. Disruptive chemicals may also contribute to multiple stages of tumor development through effects...
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- inducing methylome changes associated with oncogenic progression has been shown in lung, colorectal and
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- Creator:
- Goodson, William H., III, Lowe, Leroy, Carpenter, David O., Gilbertson, Michael, Manaf Ali, Abdul, Lopez de Cerain Salsamendi, Adela, Lasfar, Ahmed, Carnero, Amancio, Azqueta, Amaya, Amedei, Amedeo, Charles, Amelia K., Collins, Andrew R., Ward, Andrew, Salzberg, Anna C., Colacci, Annamaria, Olsen, Ann-Karin, Berg, Arthur, Barclay, Barry J., Zhou, Binhua P., Blanco-Aparicio, Carmen, Baglole, Carolyn J., Dong, Chenfang, Mondello, Chiara, Hsu, Chia-Wen, Naus, Christian C., Yedjou, Clement, Curran, Colleen S., Laird, Dale W., Koch, Daniel C., Carlin, Danielle J., Felsher, Dean W., Roy, Debasish, Brown, Dustin G., Ratovitski, Edward, Ryan, Elizabeth P., Corsini, Emanuela, Rojas, Emilio, Moon, Eun-Yi, Laconi, Ezio, Marongiu, Fabio, Al-Mulla, Fahd, Chiaradonna, Ferdinando, Darroudi, Firouz, Martin, Francis L., Van Schooten, Frederik J., Goldberg, Gary S., Wagemaker, Gerard, Nangami, Gladys N., Calaf, Gloria M., Williams, Graeme P., Wolf, Gregory T., Koppen, Gudrun, Brunborg, Gunnar, Lyerly, H. Kim, Krishnan, Harini, Ab Hamid, Hasiah, Yasaei, Hemad, Sone, Hideko, Kondoh, Hiroshi, Salem, Hosni K., Hsu, Hsue-Yin, Park, Hyun Ho, Koturbash, Igor, Miousse, Isabelle R., Scovassi, A.Ivana, Klaunig, James E., Vondráček, Jan, Raju, Jayadev, Roman, Jesse, Wise, John P., Sr., Whitfield, Jonathan R., Woodrick, Jordan, Christopher, Joseph A., Ochieng, Josiah, Martinez-Leal, Juan F., Weisz, Judith, Kravchenko, Julia, Sun, Jun, Prudhomme, Kalan R., Narayanan, Kannan B., Cohen-Solal, Karine A., Moorwood, Kim, Gonzalez, Laetitia, Soucek, Laura, Jian, Le, D’Abronzo, Leandro S., Lin, Liang-Tzung, Li, Lin, Gulliver, Linda, McCawley, Lisa J., Memeo, Lorenzo, Vermeulen, Louis, Leyns, Luc, Zhang, Luoping, Valverde, Mahara, Khatami, Mahin, Romano, Maria F., Chapellier, Marion, Williams, Marc A., Wade, Mark, Manjili, Masoud H., Lleonart, Matilde E., Xia, Menghang, Gonzalez Guzman, Michael J., Karamouzis, Michalis V., Kirsch-Volders, Micheline, Vaccari, Monica, Kuemmerle, Nancy B., Singh, Neetu, Cruickshanks, Nichola, Kleinstreuer, Nicole, van Larebeke, Nik, Ahmed, Nuzhat, Ogunkua, Olugbemiga, Krishnakumar, P. K., Vadgama, Pankaj, Marignani, Paola A., Ghosh, Paramita M., Ostrosky-Wegman, Patricia, Thompson, Patricia A., Dent, Paul, Heneberg, Petr, Darbre, Philippa, Leung, Po Sing, Nangia-Makker, Pratima, Cheng, Qiang, Robey, R. Brooks, Al-Temaimi, Rabeah, Roy, Rabindra, Andrade-Vieira, Rafaela, Sinha, Ranjeet K., Mehta, Rekha, Vento, Renza, Di Fiore, Riccardo, Ponce-Cusi, Richard, Dornetshuber-Fleiss, Rita, Nahta, Rita, Castellino, Robert C., Palorini, Roberta, Hamid, Roslida A., Langie, Sabine A. S., Eltom, Sakina E., Brooks, Samira A., Ryeom, Sandra, Wise, Sandra S., Bay, Sarah N., Harris, Shelley A., Papagerakis, Silvana, Romano, Simona, Pavanello, Sofia, Eriksson, Staffan, Forte, Stefano, Casey, Stephanie C., Luanpitpong, Sudjit, Lee, Tae-Jin, Otsuki, Takemi, Chen, Tao, Massfelder, Thierry, Sanderson, Thomas, Guarnieri, Tiziana, Hultman, Tove, Dormoy, Valérian, Odero-Marah, Valerie, Sabbisetti, Venkata, Maguer-Satta, Veronique, Rathmell, W. Kimryn, Engström, Wilhelm, Decker, William K., Bisson, William H., Rojanasakul, Yon, Luqmani, Yunus, Chen, Zhenbang, and Hu, Zhiwei
- Abstract:
- Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is between 7% and 19%. To explore the hypothesis that...
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- Article
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- Creator:
- Hu, Zhiwei, Brooks, Samira A., Dormoy, Valérian, Hsu, Chia-Wen, Hsu, Hsue-Yin, Lin, Liang-Tzung, Massfelder, Thierry, Rathmell, W. Kimryn, Xia, Menghang, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Brown, Dustin G., Prudhomme, Kalan R., Colacci, Annamaria, Hamid, Roslida A., Mondello, Chiara, Raju, Jayadev, Ryan, Elizabeth P., Woodrick, Jordan, Scovassi, A. Ivana, Singh, Neetu, Vaccari, Monica, Roy, Rabindra, Forte, Stefano, Memeo, Lorenzo, Salem, Hosni K., Lowe, Leroy, Jensen, Lasse, Bisson, William H., and Kleinstreuer, Nicole
- Abstract:
- One of the important ‘hallmarks’ of cancer is angiogenesis, which is the process of formation of new blood vessels that are necessary for tumor expansion, invasion and metastasis. Under normal physiological conditions, angiogenesis is well balanced and controlled by endogenous proangiogenic factors and antiangiogenic factors. However, factors produced by cancer...
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- Article
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- -induced MMP-1 expression in human dermal fibroblasts and p53 dysfunction caused by XPC defects in lung
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- Creator:
- Narayanan, Kannan Badri, Ali, Manaf, Barclay, Barry J., Bisson, William H., Cheng, Qiang, D'Abronzo, Leandro, Dornetshuber-Fleiss, Rita, Gosh, Paramita M., Gonalez-Guzman, Michael J., Lee, Tae-Jin, Leung, Po Sing, Li, Lin, Luanpitpong, Suidjit, Ratoviski, Edward, Rojanasakul, Yon, Romano, Maria Fiammetta, Romano, Simona, Sinha, Kumar Ranjeet, Yedjou, Clement, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Brown, Dustin G., Ryan, Elizabeth P., Colacci, Annamaria, Hamid, Roslida A., Mondello, Chiara, Raju, Jayadev, Salem, Hosni K., Woodrick, Jordan, Scovassi, Ivana, Singh, Neetu, Vaccari, Monica, Roy, Rabindra, Forte, Stefano, Memeo, Lorenzo, Kim, Seo Yun, Lowe, Leroy, and Park, Hyun Ho
- Abstract:
- Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically,...
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- identified and isolated from various solid tumors including the lung, brain, breast, colon and skin. These
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- Creator:
- Carnero, Amancio, Blanco-Aparicio, Carmen, Kondoh, Hiroshi, Lleonart, Matilde E., Martinez-Leal, Juan Fernando, Mondello, Chiara, Scovassi, A. Ivana, Bisson, William H., Amedei, Amedeo, Roy, Rabindra, Woodrick, Jordan, Colacci, Annamaria, Vaccari, Monica, Raju, Jayadev, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Salem, Hosni K., Memeo, Lorenzo, Forte, Stefano, Singh, Neetu, Hamid, Roslida A., Ryan, Elizabeth P., Brown, Dustin G., Wise, John P., Sr., Wise, Sandra S., and Yasaei, Hemad
- Abstract:
- Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically,...
- Resource Type:
- Article