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Filtering by: Alternative title ssim EM 8311 Creator Axton, Elizabeth R. Degree Name Doctor of Philosophy (Ph.D.)

Mass spectrometry techniques to assess the metabolism and toxicity of pharmaceutical and dietary nitrates

Creator:

Axton, Elizabeth R.

Abstract:

Nitric oxide (NO) is a signaling molecule that regulates blood pressure and vascular tone. Humans produce NO by endothelial nitric oxide synthase (eNOS), which is impaired in patients with cardiovascular disease leading to increased blood pressure, endothelial dysfunction, and an increased risk of adverse cardiovascular outcomes. Maintaining optimal levels of...

Resource Type:

Dissertation