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Filtering by: Creator Bai, Shaochun Creator Cummings, Oscar W. Creator Athinarayanan, Shaminie

TraberMaretPublicHealthHumanSciencesResponseAdultsChildren_SupportingInformation.zip

Creator:

Athinarayanan, Shaminie, Wei, Rongrong, Zhang, Min, Bai, Shaochun, Traber, Maret G., Yates, Katherine, Cummings, Oscar W., Molleston, Jean, Liu, Wanqing, and Chalasani, Naga

Abstract:

Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials, but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...
TraberMaretPublicHealthHumanSciencesResponseAdultsChildren.pdf

Creator:

Athinarayanan, Shaminie, Wei, Rongrong, Zhang, Min, Bai, Shaochun, Traber, Maret G., Yates, Katherine, Cummings, Oscar W., Molleston, Jean, Liu, Wanqing, and Chalasani, Naga

Abstract:

Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials, but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...
Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and TONIC Clinical Trials

Creator:

Athinarayanan, Shaminie, Wei, Rongrong, Zhang, Min, Bai, Shaochun, Traber, Maret G., Yates, Katherine, Cummings, Oscar W., Molleston, Jean, Liu, Wanqing, and Chalasani, Naga

Abstract:

Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials, but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...

Resource Type:

Article

ScholarsArchive@OSU

TraberMaretPublicHealthHumanSciencesResponseAdultsChildren_SupportingInformation.zip

TraberMaretPublicHealthHumanSciencesResponseAdultsChildren.pdf

Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and TONIC Clinical Trials

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