Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Full Text:
Role for Respiratory Metabolism
in Mediating Toxicity
Smith, M. R., Boenzli, M. G., Hindagolla, V
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Full Text:
mediating toxicity 2
3
Mark R. Smith1, Matthew G. Boenzli1, Vihangi Hindagolla1, Jun Ding1,2
Ultraviolet-protective compounds, such as mycosporine-like amino acids (MAAs) and related gadusols produced by some bacteria, fungi, algae, and marine invertebrates, are critical for the survival of reef-building corals and other marine organisms exposed to high-solar irradiance. These compounds have also been found in marine fish, where their accumulation is thought...
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.