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Filtering by: Committee Member Mason, Barbara J. Remove constraint Committee Member: Mason, Barbara J. Creator Baker, Kasie J. Remove constraint Creator: Baker, Kasie J.

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  • Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

    Creator:
    Baker, Kasie J.
    Abstract:
    The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
    Resource Type:
    Dissertation
    Full Text:
    THE DISSERTATION OF Kasie J. Baker for the degree of Doctor of Philosophy in Biochemistry and