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Filtering by: Publisher American Vacuum Society Creator Barbar, Elisar License Attribution 4.0 (CC BY 4.0)

Interactions of yeast dynein with dynein light chain and dynactin: General implications for intrinsically disordered duplex scaffolds in multi-protein assemblies

Creator:

Jie, Jing, Löhr, Frank, and Barbar, Elisar

Abstract:

Intrinsically disordered protein (IDP) duplexes composed of two IDP chains cross-linked by bivalent partner proteins form scaffolds for assembly of multiprotein complexes. The N-terminal domain of dynein intermediate chain (N-IC) is one such IDP that forms a bivalent scaffold with multiple dynein light chains including LC8, a hub protein that...

Resource Type:

Article